Masters of Science (Infectious Diseases) (Distinction) 2009 – 2012 University of London External System (London School of Hygiene & Tropical Medicine), UK Bachelor of Science (Pharmacy) (Honours) 2003 – 2007 National University of Singapore, SG Added Qualifications in Infectious Diseases 2012 Board Certified Pharmacotherapy Specialist 2011 Board of Pharmacy Specialties, US Pharmacist (Infectious Diseases) 2010 – Present
Antimicrobial stewardship (ASP) pharmacist Assist in the management of the SGH anti-infective research lab
- Oversee daily operations of the laboratory - Formulate pharmaco-therapeutic plan based on in-vitro antibiotic combination
test results as consultation service for combination testing
- Mentor pre-registration/ASP pharmacists in the conduct of ID-related research
- Train inpatient pharmacists newly rotated to ASP - Precept polytechnic students attached to anti-infective research lab
- Clinical trainer for pre-reg ID clinical sessions and pre-reg ID elective rotation
Infectious Diseases Resident 2009 –2010 Postgraduate Allied Health Institute, Singapore General Hospital Pharmacist (Antimicrobial Stewardship) 2008 – 2009
Member of the multi-disciplinary antimicrobial stewardship (ASP) team
- Key member involved in fine-tuning the work-flow when ASP was initiated
- Monitored the measurable outcomes of the program which include the rates of
appropriateness of antibiotic prescriptions, intervention acceptance rates,
antibiotic consumption and expenditures, antibiotic resistance
- Developed institutional intravenous-to-oral conversion guidelines for parenteral
- Assisted in the development of Singapore General Hospital Antimicrobial
- Contributed two infectious disease-related articles to the institutional patient
safety newsletter (Jan – Mar 2010 edition)
- Designed and executed exhibition program at 2-day PS21 Excel Convention:
public education regarding issue of antimicrobial resistance and efforts aimed at
Pharmacist in charge of infectious diseases isolation wards
Basic Principles of Antibiotic Use 2012 – present
Annual training lecture for Singapore General Hospital pre-registration pharmacists
Aminoglycoside PK, PD & TDM 2009 – present
Annual training lecture for Singapore General Hospital pre-registration pharmacists
Ertapenem: Relationship between use & resistance. 2012
Presentation for Singapore General Hospital Department of Infectious Diseases
Carbapenems Overview 2011
Presentation for SingHealth purchasing pharmacists
Antibiotics Overview 2011
In-service lecture for infectious diseases isolation ward nurses
Oral Papers YY Cai, TP Lim, J Teo, S Sasikala, N Rafida, TY Tan, W Lee, LY Hsu, TT Tan, AL Kwa.
Comparison of a Rapid Multiple Combination Bactericidal Testing method versus
Conventional Time Kill Studies for Patients Infected with Extreme Drug Resistant
Acinetobacter baumannii with Decreasing Susceptibilities to Polymyxin B. SingHealth Duke-
NUS Scientific Congress, Singapore, 2012.
MP Chlebicki, JCZ Loh, Y Liew, JQM Teo, RWQ. Ong, Y. Cai, CLL Lim, SSL Tang, W
Lee, AL Kwa. Antimicrobial Stewardship Programme in Singapore General Hospital: Is it
Safe for Our Patients? 51st Interscience Conference on Antimicrobial Agents and
Chemotherapy & Annual Scientific Meeting (ICAAC), Chicago, USA, 2011.
J Teo, TP Lim, W Lee, S Sasikala, DQ Chia, LY Hsu, TT Tan, AL Kwa. In vitro activity of
doripenem in combination with polymyxin against multidrug-resistant Acinetobacter
baumanni. 21st European Congress of Clinical Microbiology and Infectious Diseases
Teo J, Liew YX, Lim C, Lee W, Kwa AL. Use of biomarkers to guide antibiotic therapy: A
meta-analysis. SGH 19th Annual Scientific Meeting, Singapore, 2011.
J Teo, R Ong, S Tang, YY Cai, P Chlebicki, J Loh, YX Liew, W Lee. Antimicrobial
Stewardship: Optimising Antimicrobial Use in Singapore General Hospital. 12th Western
Pacific Congress on Chemotherapy and Infectious Diseases (WPCCID), Singapore, 2010.
Teo J, Lee W, Chlebicki P, Kwa ALH. Fighting the ‘Superbug’ War – Antimicrobial
Stewardship in Singapore General Hospital. 27th International Society for Quality in Healthcare Confernce, Paris, 2010.
Poster Presentations
J Teo, Y Cai, C Lim, W Lee, AL Kwa. Delineation of Specific Antibiotic (Abx) Exposures
as Risk Factors (RF) for Isolation of Carbapenem-resistant Enterobacteriaceae (CRE): A Meta-analysis. 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy &
Annual Scientific Meeting (ICAAC), San Francisco, USA, 2012.
J Teo, W Lee, AL Kwa, TH Koh, YX Liew, SS Goh, ML Ling, C Song, MP Chlebicki.
Mupirocin Resistance in Methicillin-resistant Staphylococcus aureus (MRSA) in Singapore
General Hospital (SGH) Burns Unit (BU). 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy & Annual Scientific Meeting (ICAAC), San Francisco, USA,
Y Cai, W Lee, YX Liew, C Lim, J Teo, R Ong, S Tang, MP Chlebicki, AL Kwa. The Role
of an Anti-microbial Stewardship Program (ASP) in an Adult Renal Department. 52nd
Interscience Conference on Antimicrobial Agents and Chemotherapy & Annual Scientific
Meeting (ICAAC), San Francisco, USA, 2012.
TP Lim, S Sasikala, W Lee, N Rafida, J Teo, TY Tan, LY Hsu, TT Tan, AL Kwa.
Comparative Activity of Various Antibiotics alone & in Combination against High Inocula Methicillin-Resistant Staphylococcus aureus with Reduced Susceptibilities to
Vancomycin. 22nd European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), London, UK, 2012
TP Lim, S Sasikala, W Lee, N Rafida, E Chan, YM Tan, J Teo, TY Tan, LY Hsu, TT Tan,
AL Kwa. High Dose Doripenem & Polymyxin B is Bactericidal against Extreme Drug
Resistant Acinetobacter baumannii beyond 24 hours in a Hollow Fiber Infection Model. 22nd
European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), London,
TP Lim, S Sasikala, W Lee, N Rafida, E Chan, YM Tan, J Teo, TY Tan, LY Hsu, TT Tan,
AL Kwa. High Dose Doripenem & Polymyxin B is Bactericidal against Pan-drug Resistant
Pseudomonas aeruginosa beyond 24 hours in a Hollow Fiber Infection Model. 22nd European
Congress of Clinical Microbiology and Infectious Diseases (ECCMID), London, UK, 2012
TP Lim, J Teo, W Lee, TY Tan, LY Hsu, Koh TH, TT Tan, S Sasikala, DQ Chia, N
Rafida, AL Kwa. Carbapenems in Combination with various Antibiotics against Klebsiella pneumoniae harboring New Delhi Metallobetalactamase-1 (NDM-1) in Singapore. 51st
Interscience Conference on Antimicrobial Agents and Chemotherapy & Annual Scientific
J Teo, TP Lim, W Lee, TY Tan, LY Hsu, TT Tan, S Sasikala, DQ Chia, N Rafida, AL Kwa.
In vitro activity of doripenem in combination with polymyxin against multidrug-resistant
Pseudomonas aeruginosa. 51st Interscience Conference on Antimicrobial Agents and
Chemotherapy & Annual Scientific Meeting (ICAAC), Chicago, USA, 2011.
YX Liew, J Teo, W Lee, AL Kwa. Prolonged infusions versus intermittent boluses of beta-
lactam antibiotics: a meta-analysis. 51st Interscience Conference on Antimicrobial Agents
and Chemotherapy & Annual Scientific Meeting (ICAAC), Chicago, USA, 2011.
TP Lim, J Teo, W Lee, S Sasikala, DQ Chia, TY Tan, LY Hsu, TH Koh, TT Tan, AL Kwa.
Antibiotic combinations for Klebsiella sp. harbouring New Delhi Metallo-beta-lactamase-1 in Singapore. 21st European Congress of Clinical Microbiology and Infectious Diseases
R. Ong, J Teo, WG Seetoh, MH Sim, YY Cai, S Tang, A Kwa, MP Chlebicki, W Lee. Point
prevalence survey of piperacillin-tazobactam and cefepime prescriptions in Singapore
General Hospital. International Symposium on Antimicrobial Agents & Resistance Meeting (ISAAR), Seoul, Korea, 2011.
J Teo, YY Cai, S Tang S, YX Liew, Lee W, Tan TT, AL Kwa. Risk Factors for Acquisition
of Ertapenem-Resistant Enterobacteriaceae Infections: A Case-Case-control Study. 50th
Interscience Conference on Antimicrobial Agents and Chemotherapy & Annual Scientific
Y Liew, J Teo, AL Kwa, M Chlebicki. Use of Procalcitonin (PCT) to Guide
Discontinuation of Antibiotic Use in an Antimicrobial Stewardship Program (ASP). 50th
Interscience Conference on Antimicrobial Agents and Chemotherapy & Annual Scientific
Cai YY, Teo J, Ong R, A Wang, M Chlebicki. Impact of antimicrobial stewardship
strategies on antimicrobial use. Duke-Singhealth Annual Scientific Meeting,
J Teo, Cai YY, Ong R, M Chlebicki. Antimicrobial prophylaxis for prevention of recurrent
erysipelas. Duke-Singhealth Annual Scientific Meeting, Singapore, 2010.
W Lee, J Teo, MP Chlebicki, A L Kwa. Antimicrobial Stewardship Program in Singapore
General Hospital (Department of General Surgery). 49th Interscience Conference on
Antimicrobial Agents and Chemotherapy & Annual Scientific Meeting (ICAAC), San
Teo JQM, Phuah WL, Kwa ALH et al. Intravenous-to-oral (IV-to-PO) switch regimens for
amoxicillin-clavulanate, azithromycin, ciprofloxacin, fluconazole and trimethoprim-
sulfamethoxazole in Singapore General Hospital. International Congress of Infection
Control Association (Singapore), Singapore, 2009.
Teo JQM, Kwa AL. Rapid Microbiological Eradication of Multi-Drug Resistant Acinetobacter baumannii Pneumonia with Aerosolized Colistin. 7th International Symposium on Antimicrobial Agents & Resistance Meeting (ISAAR), Bangkok, 2009.
Phuah WL, Teo JQM, Kwa ALH et al. IV-to-PO Switch Regimen For Ciprofloxacin.
Singhealth Annual Scientific Meeting, Singapore, 2008.
Liew YX, Lee W, Cai YY, Teo J, Tang SS, Ong RW, Lim CL, Lingegowda PB, Kwa AL,
Chlebicki MP. Utility and safety of procalcitonin in an antimicrobial stewardship program
(ASP) in patients with malignancies. Eur J Clin Microbiol Infect Dis. 2012 Nov; 31(11):3041-6.
Liew YX, Lee W, Loh JC, Cai Y, Tang SS, Lim CL, Teo J, Ong RW, Kwa AL, Chlebicki
MP. Impact of an antimicrobial stewardship programme on patient safety in Singapore
General Hospital. Int J Antimicrob Agents. 2012; 40(1):55-60.
Teo J, Cai Y, Tang S, Lee W, Tan TY, Tan TT, Kwa AL. Risk factors, molecular
Enterobacteriaceae: a case-case-control study. PLoS One. 2012; 7(3):e34254. Epub 2012
Teo J, Tan TY, Hon PY, Lee W, Koh TH, Krishnan P, Hsu LY; the Network for
Antimicrobial Resistance Surveillance (Singapore). ST22 and ST239 MRSA duopoly in
Singaporean hospitals: 2006-2010. Epidemiol Infect. 2012 Mar 7:1-5. [Epub ahead of print]
TP Lim, W Lee, TY Tan, S Sasikala, J Teo, LY Hsu, TT Tan, N Syahidah, Andrea L. Kwa.
Effective antibiotics in combination against extreme drug-resistant Pseudomonas aeruginosa
with decreased susceptibility to polymyxin B. PlosOne 2011; 6(12):E28177. Epub 2011 Dec
Teo J, Kwa AL, Loh J, Chlebicki MP, Lee W. The effect of a whole-system approach in an
antibiotic stewardship program at the Singapore General Hospital. Eur J Clin Microbiol
Awarded as Principal Investigator
Development of a Rapid Turnaround Method using ATP as a biomarker to Elucidate
Antibiotic Combinations against Multidrug-resistant Pseudomonas aeruginosa and New Delhi
Metallobetalactamase-1 Klebsiella pneumoniae. (Singapore General Hospital Supplementary
Molecular Epidemiology of Carbapenem-resistant Klebsiella Pneumoniae in Singapore General
Hospital. (Singapore General Hospital Supplementary Research Grant #20/2010, $30,000)
Awarded as Co-investigator/Collaborator
Utility of direct DNA extraction, fol owed by high throughput PCR and sequencing for rapid
assessment of echinocandin resistance in Candidemia. (Singapore General Hospital Supplementary Research Grant #15/2012, $30,000)
Integration of Population Pharmacokinetics, Microbiologic Surveillance Data and Drug
Acquisition Cost to Generate a Rational Empiric Dosing Strategy for Carbapenems against
Nosocomial Gram-Negative Pathogens (Singapore General Hospital Supplementary
The clinical utility of rapid ATP (adenosine triphosphate) bioluminescence-based time-kill
methodology to guide antimicrobial combination in pan-drug resistant gram-negative bacteria. (National Medical Research Council Exploratory and Developmental Grant
Impact of Antibiotic Stewardship Program on antibiotic utilization and antimicrobial
resistance in Singapore General Hospital. (Singhealth Foundation Innovation in Infection
Control Grant SHF/IIC003/2009 - $50,000)
Other research support
American Society for Microbiology Student and Post-doctoral Fellow Travel Grant Award
Scientific Awards
SingHealth Duke-NUS Scientific Congress Best Poster Award (Allied Health) 2012
“Antibiotic Combinations for Klebsiella pneumoniae harbouring New Delhi Metallo-β-lactamase-1
SIDS Practice Update Best Poster Award (1st Prize) 2012
“Prolonged infusions versus intermittent boluses of beta-lactam antibiotics: a meta-analysis.”
SIDS Practice Update Best Poster Award (3rd Prize) 2012
“Carbapenems in combination with various antibiotics against Klebsiella pneumoniae harbouring New Delhi metallobetalactamase-1 in Singapore”
SingHealth Duke-NUS Scientific Congress Best EBM Poster Award (Allied Health) 2010
“Impact of antimicrobial stewardship strategies on antimicrobial use.”Clinical Practice Improvement Awards
Singhealth Allied Health Innovative Practice Awards Winner 2012
“Synergy – Antimicrobial Combination Susceptibility Testing For Drug-resistant Infections”
Asian Hospital Management Awards Patient Safety Excellence Award 2010
“Antimicrobial Stewardship in Singapore General Hospital”
Singapore General Hospital Quality Improvement Project of the Year 1st Runner-up 2010
“Fighting the Superbug War - Antimicrobial Stewardship”
Singhealth Allied Health Innovative Practice Awards Winner 2009
London School of Hygiene & Tropical Medicine MSc ID Martin Taylor Award 2013
Singapore Health Quality Service Award - Silver 2012
Society of Infectious Diseases, Singapore (SIDS) American Society of Microbiology (ASM)
European Society of Clinical Microbiology and Infectious Diseases (ESCMID)
Pharmacy Clinician Scientist, Singapore General Hospital
Senior Consultant, Department of Infectious Diseases, Singapore General Hospital
K. W. Liu et al . • CMV infection may be a risk factor for venous 4. Myerson D, Hackman RC, Nelson JA, McDoughall JK. Wide- thromboembolism and prophylaxis of this should bespread presence of histologically occult cytomegalovirus. Hum 5. Jenkins RE, Peters BS, Pinching AJ. Thromboembolic disease in AIDS is associated with cytomegalovirus disease. AIDS Conflicts of interest 6. M
COLÉGIO MILITAR FELICIANO NUNES PIRES Técnicas de Redação Professora Michela Ribeiro Espíndola Material de apoio de estudo Série: 6ª série Evite a 'ressaca' de chocolate nesta Páscoa Evite os males do exagero do chocolate neste feriado Foto: Getty Images O período favorito do ano de todo chocólatra chegou: a Páscoa! Porém, se você já está temendo o pós