Central nervous system depressants

CENTRAL NERVOUS SYSTEM DEPRESSANTS
Opioid Pain Relievers
Anxiolytics (also belong to psychiatric
medication category)
• codeine (in 222® Tablets, Tylenol® No. 1/2/3/4, Fiorinal® C,
Benzodiazepines
• heroin
• alprazolam (Xanax®)
• hydrocodone (Hycodan®, etc.)
• chlordiazepoxide (Librium®)
• hydromorphone (Dilaudid®)
• clonazepam (Rivotril®)
• methadone
• diazepam (Valium®)
• morphine (MS Contin®, M-Eslon®, Kadian®, Statex®, etc.)
• flurazepam (Dalmane®)
• oxycodone (in Oxycocet®, Percocet®, Percodan®, OxyContin®, etc.)
• lorazepam (Ativan®)
• pentazocine (Talwin®)
• nitrazepam (Mogadon®)
• oxazepam ( Serax®)
• temazepam (Restoril®)
Inhalants
Barbiturates
gases (e.g. nitrous oxide, “laughing gas”, chloroform, halothane,
• butalbital (in Fiorinal®)
• secobarbital (Seconal®)
volatile solvents (benzene, toluene, xylene, acetone, naptha and
hexane)
Buspirone (Buspar®)
nitrites (amyl nitrite, butyl nitrite and cyclohexyl nitrite – also known
as “poppers”)
Non-Benzodiazepine Hypnotics (also
belong to psychiatric medication category)
• chloral hydrate
• zopiclone (Imovane®)
• GHB (gamma-hydroxybutyrate)
• Rohypnol (flunitrazepam)
CENTRAL NERVOUS SYSTEM STIMULANTS
Amphetamines
Caffeine

• dextroamphetamine (Dexadrine®)
Methelynedioxyamphetamine (MDA)
• methamphetamine (“Crystal meth”)
• methylphenidate (Biphentin®, Concerta®, Ritalin®)
• mixed amphetamine salts (Adderall XR®)
3,4-Methelynedioxymethamphetamine (MDMA, Ecstasy)
(also has hallucinogenic actions)
Cocaine/Crack
Nicotine
Decongestants (alone or in combination with other
medications in allergy and cough and cold
products)
• phenylephrine
• pseudoephedrine (Sudafed®)
Herbal Stimulants (e.g. ephedra)
HALLUCINOGENS
Indolealkylamines
Cannabinoids
(especially “THC”/tetrahydrocannabinol, found in marijuana, hash,
• DMT (Dimethyltryptamine, from the bark of the Virola
• LSD (d-lysergic acid diethylamide, “Acid”)
• LSA (d-lysergic amide, from morning
Anticholinergics
• psilocybin (“Magic mushrooms”)
• deadly nightshade (Atropa belladonna)
• jimsonweed (Datura stramonium)
• scopolamine (Transderm-V®)
Phenylethylamines
Arylcycloalkylamines
• mescaline (found in peyote cactus)
• MDA (Methylenedioxyamphetamine)
• ketamine
• MDMA (Ecstasy, 3,4-methylenedioxymethamphetamine)
• PCP (Phencyclidine)
• PMA (Paramethoxyamphetamine)
• 2-CB (4-bromo-2,5-dimethoxyphenethylamine)
Salvinorin-A (from the plant Salvia divinorum)
• STP (2,5-dimethoxy-4-methylamphetamine)
• TMA (Trimethoxyamphetamine)
PSYCHIATRIC MEDICATIONS
Antipsychotics
Antidepressants
Typical (oral)
Tricyclic Antidepressants (TCAs)
• chlorpromazine (Largactil®)
• amitriptyline (Elavil®)
• flupenthixol (Fluanxol)
• clomipramine (Anafranil®)
• fluphenazine (Modecate®)
• desipramine (Norpramin®)
• haloperidol (Haldol®)
• doxepin
• loxapine
• imipramine (Tofranil®)
• methotrimeprazine (Nozinan®)
• nortriptyline (Aventyl®)
• perphenazine (Trilafon®)
• trimipramine (Surmontil®)
• pimozide (Orap®)
• trifluoperazine (Stelazine®)
Monoamine Oxidase Inhibitors (MAOIs)
• zuclopenthixol (Clopixol®)
• moclobemide (Manerix®)
• phenelzine (Nardil®)
Atypical (oral)
• tranylcypromine (Parnate®)
• aripiprazole (Abilify®)
Selective Serotonin Reuptake Inhibitors (SSRIs)
• clozapine (Clozaril®)
• olanzapine (Zyprexa®/Zyprexa® Zydis/Zyprexa®
• citalopram (Celexa®)
• escitalopram (Cipralex®)
• paliperidone extended release tablet (Invega®)
• fluoxetine (Prozac®)
• quetiapine (Seroquel®/Seroquel® XR)
• fluvoxamine (Luvox®)
• risperidone (Risperdal®/Risperdal® M-Tab/Risperdal®
• paroxetine (Paxil® and Paxil CR®)
sertraline (Zoloft®)
ziprasidone (Zeldox®)
Selective Serotonin and Norepinephrine Reuptake
Depot (long-acting) antipsychotic injections
Inhibitors (SNRIs)
• flupenthixol decanoate (Fluanxol® Depot)
• desvenlafaxine (Pristiq®)
• fluphenazine decanoate (Modecate® Depot)
• duloxetine (Cymbalta®)
• haloperidol decanoate (Haldol® Depot)
• venlafaxine (Effexor® XR)
• paliperidone palmitate long acting injection
Serotonin-2 Antagonists/Reuptake Inhibitor (SARI)
• pipotiazine palmitate (Piportil® Depot)
• risperidone (Risperdal® Consta)
trazodone (Desyrel®)
zuclopenthixol acetate (Clopixol® Accuphase)
• zuclopenthixol decanoate (Clopixol® Depot)
Norepinephrine and Dopamine Reuptake Inhibitors
(NDRIs)
Antiparkinsonian Agents
(for treatment of extrapyramidal side effects of
• bupropion SR (Wellbutrin® SR)
antipsychotics)
• bupropion XL (Wellbutrin® XL)
• benztropine (Cogentin®)
Noradrenergic/Specific Serotonergic Antidepressants
• biperiden
(NaSSAs)
• ethopropazine
• procyclidine (Kemadrin®)
mirtazapine (Remeron®)
trihexyphenidyl (Artane®)
• mirtazapine orally disintegrating tablet (Remeron
Non-Benzodiazepine Sedative/Hypnotics
(also belong to CNS depressants category)
Mood Stabilizers
• chloral hydrate
• carbamazepine (Tegretol®)
• zopiclone (Imovane®)
• lamotrigine (Lamictal®)
• lithium (Carbolith®)
Agents for Alcohol Dependence
• topiramate (Topamax®)
• valproic acid/divalproex (Epival®)
• acamprosate (Campral®)
• disulfiram (Antabuse®)
Adjunct in the treatment of mood disorders
• naltrexone (Revia®)
• L-tryptophan (Tryptan®)
Agents for Smoking Cessation
Anxiolytics
• nicotine (patch, gum, lozenge, inhaler)
(also belong to the CNS depressants category)
• varenicline (Champix®)
Benzodiazepines
• bupropion SR (Zyban®)
• alprazolam (Xanax®)
Opioid Substitution Therapy
• chlordiazepoxide (Librium®)
• clonazepam (Rivotril®)
• buprenorphine with naloxone (Suboxone®)
• diazepam (Valium®)
• methadone
• flurazepam (Dalmane®)
• lorazepam (Ativan®)
Opioid Antagonists
• nitrazepam (Mogadon®)
• oxazepam ( Serax®)
• naloxone (Narcan®)
• temazepam (Restoril®)
Barbiturates
• butalbital (in Fiorinal®)
• secobarbital (Seconal®)
Buspirone (Buspar®)

Source: http://knowledgex.camh.net/health_equity/interpreters/Documents/New_Drug_Chart_Glossary_November_2011.pdf