ANTICHOLINERGIC COGNITIVE BURDEN SCALE
Developed by the Aging Brain Program of the IU Center for Aging Research
Drugs with Possible Anticholinergic Effects Drugs with Definite Generic Name Brand Name Generic Name Brand Name Complete References:
Boustani MA, Campbell NL, Munger S, Maidment I, Fox GC. Impact of anticholinergics on the
aging brain: a review and practical application. Aging Health. 2008;4(3):311-20.
2. Campbell N, Boustani M, Limbil T, Ott C, et al. The cognitive impact of anticholinergics: a
clinical review. Clinical Interventions in Aging. 2009;4(1):225-33
6/27/12 - Do not reproduce without permission – conta
The following represents a list of alternative medications developed by an
The following represents a list of alternative medications developed by an
interdisciplinary group of specialists within the Aging Brain Program at Indiana
interdisciplinary group of specialists within the Aging Brain Program at Indiana
University. These suggestions do not supersede clinical judgment, and are intended to
University. These suggestions do not supersede clinical judgment, and are intended to
assist clinicians in practicing in acute health care settings who provide care for patients
assist clinicians in practicing in acute health care settings who provide care for patients
with cognitive impairment such as dementia, mild cognitive impairment or delirium.
with cognitive impairment such as dementia, mild cognitive impairment or delirium.
Recommended alternatives to medications with Definite Anticholinergic Properties
Recommended alternatives to medications with Definite Anticholinergic Properties Allergies or itching: Hold during acute care stay – consider Loratadine or Cetirizine orally scheduling toileting Insomnia: Trazadone orally Reflux disorders: Esomeprazole orally (Clinical judgment to consider if Painful abdominal cramps: Morphine orally or IV Depression: Sertraline or Citalopram orally Neuropathic pain: Consider ondansetron IV or PO, or Gabapentin orally Metoclopramide PO Insomnia: Trazadone orally Acetaminophen or oxycodone/ (Recommendation does not apply to acetaminophen chronic use for psychiatric diagnosis) Acute care environment: Morphine sulfate orally or IV Haloperidol orally or IM for 72 hours only Seizures: Consult neurology for alternative Neuropathic pain: Gabapentin or levetiracetam orally Movement disorders: Mood disorders: Dopamine agonists or levodopa Consult psychiatry for alternative For more information or permission to duplicate, please contact: Noll Campbell, PharmD or Malaz A. Boustani, MD, MPH Regenstrief Institute, Inc./IU Center for Aging Research 6/27/12 - Do not reproduce without permission – contact 410 West 10th Street, Suite 2000 Indianapolis, IN 46202-3012 www.indydiscoverynetwork.com Phone: (317) 423-5633 Fax: (317) 423-5695
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