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Swami Ramanand Teerth Marathwada University,
B. O. S. In Chemistry
B. Sc. Second Year (Dyes and Drugs)
Revised Syllabus
In force from June - 2009
B. Sc. Second Year
DYES AND DRUGS
s/week Periods
B.Sc. IIyear
DYES AND DRUGS
Paper: IV (CHDD-201)
Study and synthesis of dyes
Periods:

UNIT I

I. Azo-Dyes – Synthesis and applications :
10 periods
(viii) Aniline yellow (ix) Butter yellow (xi) Diamond black F (xii) Chromotrope 2B (xiii) Erichrome black T
II. Dyeing and fastness properties of azo dyes
10 periods
i. General consideration ii. Dyeing and fastness properties of a.

UNIT II
I Azoic Dyes :

14 periods

Introduction,. Chemical constitution of napthols, preparation of Napthols, Napthols for yellow
shade, azoic shades, steps involved in azoic dyeing, application of azoic dyes on fibres other than
cotton (wool, silk, cellulose, acetate) fastness properties of azoic shades top light, chlorine,,
rubbing, alkali, azoic colours in printing, printing composition. Types of azoic colours in
printing.

II.

Heterocyclic
6 periods

Introduction, Classification, Synthesis and applications of
1. Indophenol blue
UNIT III

I. Diphenyl and triphenyl methane dyes :
12 periods

1. Diphenyl methane dyes : Introduction, synthesis and application of Auramine O and
Auramine G
2. Triphenyl methane dyes : Introduction. Classification, General properties, constitution of
Triphenyl methane dyes (w.r.t. pararosaniline)
3. Synthesis and applications of following triphenyl methane dyes
a. Malachite green
4. Phenolphthalein – Synthesis, properties and application.
II. Anthraquinone Dyes :
8 periods

Introduction, classification, synthesis and applications of dyes
1. Alizarin

UNIT IV
I.

Xanthene
8 periods

Introduction, General properties synthesis and applications of
1. Fluorescein

II. Pigments
12 periods
a. Introduction b. Use of synthetic organic pigments c. Requirements of organic pigments d. Types of pigments e. Methods of pigment prinking f. Styles of printing g. Pigment printing, advantages and disadvantages of pigment application h. Chemical nature of pigments i. Binders and fixers, thickners. B.Sc. II year
DYES AND DRUGS
Paper: V (CHDD-202)
Study and synthesis of Drugs, their applications and physiological effects 
Periods:

UNIT I

I Study of analgesics, antipyretics and anti inflammatories
10 periods
Introduction, classification, Mechanism of action of an analgesics and antipyretics, synthesis
and applications of Acetaniline, Novalgin, Phenacetin, Paracetamol, Aspirin, salol, Irgaphyrin,
Ibuprofen, Oxyphenyl butazone
II. Study of sedatives and hypnotics
10 periods
Introduction, Classification, synthesis and applications of tchlorovynyl, chloral, Paraldehyde,
Sulphonal, Novonal, trichloroethyl urethene, phenobarbitone, Pentabarbitone

UNIT II

I.
Sulphonamides
10 periods
Introduction, discovery, classification, mechanism of action of sulpha drug, Synthesis and
applications of following sulphonamides
Sulphanilamide, Sulphapyridine, sulphadiazine, Sulphamerazine, Sulphamezathine,
Sulphamethazazole, Succinyl Sulphathiazole, Sulphaceamide, suphamylon
II. Antimalerials
10 periods
1. Introduction, historical background, Classification
2. Pathogenecity and Chemotherapy of malarial parasite
3. Study of the following antimalerials with uses : Camaquine, mepacrine, azacrine, paludrine

UNIT III
I. Anaesthetics

10 periods
Introduction, Classification, study of ether, ethylen divinylether, methyl-n-propyl ether,
Cyclopropane, Nitrous oxide, Chloroform, fluoethane, trichloroethylene, viadril
Local anaesthetics - α - Eucatine, β - Eucaine, orthocaine, Benzocaine, procaine
II.
Antiseptics
10 periods
Introduction, standardization of disinfactant (Phenol coefficient) classification
Study of following antispetics, alcohols, formaldehyde, Urotropine, metal containing antiseptics,
chlorine, chloramines (ChloramineT, Dichloroamine T, Halazone, Chloroazodin) Iodoform,
Vioform, Thymol, Dettol, Nitrofurazone

UNIT IV
I. Antibiotics

20 periods
Introduction, history of discovery, classification., study of following antibiotics with an introduction, production, isolation, properties, clinical uses and mechanism of action of penicillin, streptomycin, chloramphinicol, tetracycline Types of penicillin, structure, activity, relationship of chlormphinicol and penicillin B.Sc. IIyear
DYES AND DRUGS
Paper: VI
LABORATORY COURSE III (CHDD-203)
Periods:
(Any sixteen experiments are to be covered)
1. Preparation of dye intermediates
2. Preparation of dyes :
3. Estimation of following Aryl amines by using NaNO2 solution
4. Dyeing methods
a. Direct dyeing of wool and silk with Orange II b. Direct dyeing of wool and silk with Eosin c. Direct dyeing of wool and silk with Malachite green d. Direct dyeing of wool and silk with Crystal violet e. Direct dyeing of cotton with congo red f. Dyeing of cotton with Malachite green by Mordant dyeing method h. Dyeing of cotton by vat dyeing method B.Sc. IIyear
DYES AND DRUGS
Paper: VII
LABORATORY COURSE IV (CHDD-204)
Periods:
(Any sixteen experiments are to be covered) 1. Preparation of Drug Intermediates
2. Preparation of Drugs
3. Assay of Drugs
4. Tests for Identity and purity of Drugs
Analgin, Aspirin, Vitamin C, Pencillin G, Chlorocresol, Chloroform, Chloroquine phosphate, Cresol, Erythromycin, Isoniazide, sulphadiazine 5. Limit tests for chloride and sulphate for three drug samples 6. Qualitative Tests

Source: http://srtmun.digitaluniversity.ac/WebFiles/B.Sc.S.Y.-Syllabus-DyesandDrugs.pdf

Microsoft word - d de groote_biblio2012.docx

PubMed referenced articles 1. Patient-derived fibroblasts indicate oxidative stress status and may justify antioxidant therapy in OXPHOS disorders. Voets AM, Lindsey PJ, Vanherle SJ, Timmer ED, Esseling JJ, Koopman WJ, Willems PH, Schoonderwoerd GC, De Groote D , Poll-The BT, de Coo IF, Smeets HJ. Biochim Biophys Acta. 2012 Jul 13;1817(11):1971-1978. 2. Effect of the Intake of Resveratrol,

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