Das pharmakologische Profil von Sildenafil zeigt neben der PDE5-Inhibition auch eine geringe Aktivität an der PDE6 in der Retina. Dies erklärt visuelle Nebenwirkungen wie Farbsehstörungen, die gelegentlich auftreten. Die orale Bioverfügbarkeit beträgt etwa 40 %, mit einer hohen Bindung an Plasmaproteine. Das Verteilungsvolumen ist groß, sodass die Substanz rasch in verschiedene Gewebe gelangt. Die Metabolisierung erfolgt hepatisch und produziert einen aktiven Metaboliten, der die pharmakologische Wirkung ergänzt. Nebenwirkungen sind dosisabhängig und umfassen Kopfschmerzen, Hautrötung und Dyspepsie. Bei Vergleichen innerhalb der Wirkstoffklasse wird viagra original regelmäßig als Beispiel für eine Substanz mit schneller, aber kurzzeitiger Wirkung aufgeführt.

Microsoft word - read n share december 2009.doc

Join us at our next Read ‘n Share meeting on
Thursday February 18th at 7:30
Bring a list of Titles and Authors you have enjoyed and find out what others are reading

Read ‘n Share Titles

December 17, 2009 Meeting
The Five People You Meet in Heaven - Killed in an accident, an elderly man
discovers that heaven is having five people explain the meaning of his life.
Missing - After a businessman is murdered in Stockholm, a homeless woman
finds herself to be the prime suspect and must try to clear her name.
The Uncommon Reader - What would happen if Queen Elizabeth, at the age of
70-something, was suddenly to become a voracious reader?
Day After Night – Set in an immigrant holding camp in 1945 Palestine where four
women, refugees from Nazi Europe, find healing in the bonds of friendship.
Stephanie Plum Series – This mystery series features a sassy, New Jersey
bounty-hunter who is assisted by her eccentric grandmother and friends.
The Glassblower of Murano – A woman leaves London for a new life as a
glassblower in Venice to find her fate inextricably linked with her ancestor's.
Hotel on the Corner of Bitter and Sweet – A Chinese American widower reflects
on growing up in WWII Seattle and his forbidden relationship with a Japanese
girl.
Paradise Park – Abandoned by her boyfriend in Honolulu, Sharon Spiegelman
embarks on a quest for enlightenment.
A Reliable Wife – In 19th century Wisconsin, a troubled businessman’s ad for a
wife is answered by a woman who has her own dark secrets.
Someone Knows My Name – The life story of an African woman who is
kidnapped into slavery in the 1700s.
Warriors Series – The adventures of wild cat clans as they try to survive in a
dangerous world.
The Girl with the Dragon Tattoo- Set in Sweden, a journalist and a Goth hacker
team up to investigate a 40 year old disappearance.
Foreign Tongue – Recovering from a broken heart in Paris, a writer becomes
intrigued by the anonymously written, erotic novel she is translating.
Hatchet – After a plane crash, thirteen-year-old Brian spends fifty-four days in
the wilderness, learning to survive.
Baking Cakes in Kigali – In genocide-stricken Rwanda, a baker provides
decadent confections and transforming counsel to a series of troubled customers.
Shanghai Girls – Sold to California suitors, sisters from Shanghai struggle to
adapt to life in 1930s Los Angeles, while still bound to old customs.
The Help – 1962 Jackson, Mississippi, three women (two African-American
maids and a young white woman) team up for a clandestine project.
Half Broke Horses – A novel based on the life of the author's grandmother, who
learned to break horses in childhood and went on to run a vast ranch in Arizona.
Non- Fiction
Have a Little Faith – Albom tells the story of two men of faith, an elderly rabbi
from his home synagogue and an African-American pastor in Detroit.
Double Crossed – A journalist’s report on of the mistreatment of nuns by the
Catholic Church.
You Better Not Cry – Burroughs tells stories of his dysfunctional Christmases,
both past and present.
The Year We Disappeared – An account of a police officer who was shot in
1979 and the aftermath, told by both he and his daughter who was 9 at the time. The Necklace – The true story of thirteen women who purchased an expensive
diamond necklace together and the effect this had on their lives.
True Compass – In this autobiography, the late senator Ted Kennedy tells of his
family and his career.
Winter Dance– An account of the author’s participation in the 1,100-mile-long
dogsled race called the Iditarod.
Vanished Smile – The story of the brazen 1911 theft of the Mona Lisa from the
Louvre and the two-year quest to bring her home.

Source: http://www.eastmeadow.info/books/ReadnShareDec09titles.pdf