Das pharmakologische Profil von Sildenafil zeigt neben der PDE5-Inhibition auch eine geringe Aktivität an der PDE6 in der Retina. Dies erklärt visuelle Nebenwirkungen wie Farbsehstörungen, die gelegentlich auftreten. Die orale Bioverfügbarkeit beträgt etwa 40 %, mit einer hohen Bindung an Plasmaproteine. Das Verteilungsvolumen ist groß, sodass die Substanz rasch in verschiedene Gewebe gelangt. Die Metabolisierung erfolgt hepatisch und produziert einen aktiven Metaboliten, der die pharmakologische Wirkung ergänzt. Nebenwirkungen sind dosisabhängig und umfassen Kopfschmerzen, Hautrötung und Dyspepsie. Bei Vergleichen innerhalb der Wirkstoffklasse wird viagra original regelmäßig als Beispiel für eine Substanz mit schneller, aber kurzzeitiger Wirkung aufgeführt.

Pharmacy task force for alternate care facilties (acf)

Pharmacy Task Force for Alternate Care Facilties (ACF) Unit of Issue
Drug (Generic Name, Strength; Form)
Category
(Box, bulk, etc.)
Nitroglycerin Injection, 5mg/mL; 10mL; IV Nitroglycerin Tablets, 0.4mg; 25/vial; SL Isosorbide Mononitrate, Tablets, 30mg; PO Isosorbide Mononitrate, Tablets, 60mg; PO Enoxaparin Sodium, Injection, 30mg/0.3ml; SQ Enoxaparin Sodium, Injection, 40mg/0.4ml; SQ Enoxaparin Sodium, Injection, 60mg/0.6ml; SQ Enoxaparin Sodium, Injection, 80mg/0.8ml; SQ Enoxaparin Sodium, Injection, 100mg/1mL; SQ Enoxaparin Sodium, Injection, 120mg/0.8mL; SQ Hydrochlorothiazide, Tablets, 12.5mg; PO Hydrocodone Bitartrate/APAP 5mg-500mg tabs; PO Ibuprofen, Oral Suspension, 20mg/mL; 120mL; PO Acetaminophen, Oral Liquid, 32mg/mL; 120mL; PO Prochlorperazine, Suppositories, 25mg; PR Prochlorperazine, Injection, 5mg/mL, 2mL; IV Albuterol HFA, 90mcg MDI, 8.5gm; Inhalation Aerochamber (with and without mask/various sizes) Triamcinolone Acetonide, MDI, 20gm; Inhalation Ipratropium Bromide, 0.02% Soln., 2.5mL; Inhalation Ipratropium Bromide, MDI, 14.7gm; Inhalation Salmeterol, Inhalation Powder, MDI, #28; Inhalation Methylprednisolone, Injection, 125mg/2mL; IV Oseltamivir, Suspension, 12mg/mL; 25mL; PO Metronidazole, Injection 5mg/1mL; 100mL; IV Clindamycin, Solution, 15mg/mL; 100mL; PO Bacitracin Ointment, 500U/gm, 14.17gm; Topical Neo/Polym/Bacitracin, Ointment, 30gm; Topical Fluconazole Suspension, 10mg/mL, 35mL; PO Fluconazole Suspension, 40mg/mL, 35mL; PO Bismuth Subsalicylate, Suspension, 17.5/mL, 240mL; PO Magnesium Citrate, Oral Solution, 1.75g/30mL; 300mL; Phenytoin Sodium, Oral Suspension, 125mg/mL; 237mL; Dilantin PO Phenytoin Sodium, Capsules, 100mg; PO Sumatriptan Succinate, Tablets, 25mg; PO Sumatriptan Succinate, Tablets, 50mg; PO Sumatriptan Succinate, Tablets, 100mg; PO Fentanyl Citrate, Injection, 50mcg/mL, 5mL; IV Fentanyl, Dermal Patches, 25mcg; Topical Fentanyl, Dermal Patches, 50mcg; Topical Fentanyl, Dermal Patches, 75mcg; Topical Guaifenisen-Codeine, Elixir, 20mg-2mg/mL, 118mL; PO Acetaminophen/Codeine, Tablets, 300/30mg; PO Diphenhydramine, Elixir, 2.5mg/mL, 120mL; PO Diphenhydramine, Injection, 50mg/mL; 1mL; IV Trimethoprim/Polymyxin B, 10mL; Ophthalmic Polytrim Phenylephrine 2.5%, Solution, 5mL; Ophthalmic Naphazoline 0.1%, Solution, 15mL; Ophthalmic Fluorescein Sod Opthalmic Strips (Fluorets) Erythromycin 0.5%, Ointment, 3.5gm; Ophthalmic Lidocaine/Epinephrine, 1% Soln, 30mL; IV Epinephrine, Adult Emergency Pen, 0.3mg; IM Epinephrine, Pediatric Emergency Pen, 0.15mg; IM Vaccine, Tetanus, Diphtheria, aPertussis (DTaP), 0.5mL; Daptacel Vaccines IM Vaccine, Tetanus, Diphtheria, aPertussis (Tdap), 0.5mL; Dextrose 5% Sodium Chloride 0.45% 1000ml Sterile Water for injection, 10mL , IV (Reconstitution) Sodium Chloride for injection, 0.9%, 10mL; IV PEDS FORMULARY
Amoxicillin-Clav. Susp., 40mg-5.7mg/mL; 100mL; PO Augmentin Antibiotic Amoxicillin-Clav. Susp., 80mg-11.4mg/mL; 100mL; PO Augmentin Antibiotic Amoxicillin Suspension, 50mg/mL, 150mL; PO Antipyrene/Benzocaine, Solution, 15mL; Otic Bacitracin w/ Zn, Ointment, 500U/gm, 28.4gm; Topical Polymyxin B/Neomycin/Hydrocortisone, Susp., 10mL; Otic Zinc Oxide, Ointment, 30gm; Topical Erythromycin ES, Susp., 40mg/mL, 480mL; PO Guaifenesin-DM, Syrup, 20mg-2mg/mL, 120mL; PO Hydrocortisone 1%, Cream, 28.4gm; Topical Prochlorperazine, Pediatric Supp, 5mg; PR Trimeth:Sulfa, Suspension, 40mg:8mg/mL, 480mL; PO Loperamide, Pediatric Susp., 1mg/5mL, 120mL; PO

Source: http://www.apctoolkits.com/documents/kingcountyhc/ACFFormulary.pdf