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fluctuate during the menstrual cycle.
These natural steroids create the perfectenvironment for fertilization and celldivision at the time of conception. They
Studies reveal that women who use transdermal progesterone
cream experienced an average 7-8% bone mass density
increase in the first year, 4-5% the second year and 3-4% the
cycle and female reproductive cycle.
When insufficient amounts of
third year! Natural progesterone stimulates the production of
bone building osteoblasts, thus providing needed protection
overabundance of estrogen painfulsigns and symptom occur, categorically
against the development of osteoporosis.(1-4)
described as PMS (Pre-MenstrualSyndrome). Women suffering from the
Women taking estrogen by itself are six times more likely to
develop uterine cancer because of over-stimulation and growth
of the uterus and one and a half times more likely to develop
symptoms, some of which include waterretention, bloating, tenderness of the
breast cancer within the next five years.(5-8) Progesterone, on
the otherhand, reduces the risk by controlling estrogen levels
irritability, emotional instability,depression, and unexplainable mood
and calming uterine stimulation. Many physicians are now
recommending that progesterone be taken by all women on
estrogen as a protection against osteoporosis, (9-11) uterine
overabundance of estrogen then thesigns and symptoms of PMS often
"Harnassing the Forces of Life"
Women, too, who have entered the time of life commonly refereed
SCANTY OR IRREGULAR MENSTRUAL CYCLE.
to as “the change of life” or menopause experience similar symptomsas-well-as vasomotor flushes (hot flashes), osteoporosis, night
Small amounts (approximately ¼ teaspoon)
sweats, vaginal dryness, and mood swings. These same signs and
of progesterone should be applied 2 times a day
symptoms can be experience by women who have had a
until menstrual cycle begins. Discontinue
progesterone use during menstruation andresume use once menstruation has stopped.
Whether it be PMS or menopause, progesterone plays an
For all menstrual problems it is important to
important role in pain relief and physiological equilibrium.
PUREGEST should be taken under the supervision of a Health Care
PRE-MENSTRUAL SYNDROME (PMS)
WHO SHOULD USE NATURAL PROGESTERONE?
The most effective time to use progesterone
Women who experience scanty or irregular menstrual cycles,
is from the time of ovulation (ovulation usuallybegins 12 - 14 days from the beginning of
women that regularly suffer the pangs of PMS, and women undergoing
the “change of life,” are the top candidates for progesterone use.
menstrual cycle. Apply 1/8 teaspoon 2 times a
Before beginning a program that includes the use of progesterone, it
day for the first 4 days following ovulation. Days
is recommended that a woman seek out the advice of a Health Care
5-10 apply ¼ teaspoon 2 times a day. Days 11
until beginning of menstrual cycle apply ½teaspoon 2 times a day. Be sure to establish
WHEN SHOULD NATURAL PROGESTERONE BE USED?
your own personalized schedule by keeping anaccurate record on the calendar.
Although the amount of progesterone required by each individual
can fluctuate tremendously, certain criteria can be followed in
establishing a personalized program of health care. To produce the
menstrual cycle, progesterone may be applied to
best results it is recommended that PUREGEST be used while under
the lower abdomen. Migraines require small
the care of a Health Care Professional. The following information and
amounts of progesterone to be applied to the
dose schedules are merely general recommendations and are not
back of the neck and in the temple area.
suggested to be a cure of any pathology or disease.
“THE CHANGE OF LIFE” - MENOPAUSE
WHERE SHOULD NATURAL PROGESTERONE BE APPLIED?
For best results ¼ to ½ teaspoon 2 times a
Progesterone creams are best absorbed when applied to areas of
the body that are covered with thin layers of skin. These areas
diminished yet still present then progesteroneshould be discontinued during menstruation and
include the chest, breasts, lower abdomen, the inner portions of the
continued again after it ends. From end of
thighs and arms, wrists, and neck. For best results be sure to rotate
menstrual cycle and for the next 7 days apply ¼
areas of application, perhaps starting with the neck during the first
teaspoon 2 times a day. On the 8th day until
week, moving on to the chest the following week, and onto the lower
menstrual cycle begins apply ½ teaspoon 2
abdomen the third week. Such a rotation can also be done on a
monthly cycle, the important thing is that a routine be established. It
is not necessary to apply progesterone cream to all absorbable areas
alleviated by applying ¼ teaspoon every 15
in a cyclical pattern, only a few will suffice.
OSTEOPOROSIS AND BRITTLE BONES
Some relief may be possible by applying ¼
directed by a Health Care Professional.
1. Prior, J.C. 1990. Progesterone as a bone-tropic hormone. Endocr Rev 11:386-98.
2. Stevenson, J.C., K.F. Ganger, et al. 1990. Effects of transdermal versus oral hormone replacement therapy on bonedensity in spine and proximal femur in postmenopausal women. Lancet 336:265-26.
3. Hileman, Beth. 1994. Reproductive estrogens linked to reproductive abnormalities, cancer. Chemical and Engineering
Professional is to reach the point of equilibrium.
News, January 31:19-23.
4. Prior, Y.M. Vigna, S.I. Barr, C. Rexworthy, B.C. Lentle. Cyclic medroxyprogesterone treatment increases bone density: A
This may require that progesterone applications
controlled trial in active women with menstrual cycle disturbances. American Journal of Medicine, 1994(June);96(6):521-
be altered and tailored to the needs of each
5. Bergkvist, L., H.O. Adami, I. Perrson, R. Hoover, and C. Schairer. 1989. The risk of breast cancer after estrogen and
estrogen-progestin replacement. New England Journal of Medicine 321:293-97.
6. Tribble, D.L., and E. Frank. 1994. Dietary antioxidants, cancer, and atherosclerotic heart disease. W J Med 161:605-12.
7. Henderson, B.E., R.K. Ross, M.C. Pike, and J.T. Casagrande. 1982. Endogenous hormones as a major factor in humann
reoccur then the use of progesterone may again
8. The Journal of Epidem. 1994(April);139(7):670-683.
9. Prior, J.C., Y.M. Vigna, and N. Alojado. 1991. Progesterone and the prevention of osteoporosis. Canadian Journal of
Obstetrics/Gynecology & Women’s Health Care 3:178-84.
10. Lee, J.R. M.D., 1990. Osteoporosis reversal: the role of progesterone. Intern Clin Nutr Rev 10:384-91.
11. Lee, J.R. M.D., 1990. Osteoporosis reversal with transdermal progesterone (letter). Lancet 336:1327.
ANGIOTENSIN II BLOCKERS & COMBINATIONS eprosartan, irbesartan, irbesartan/HCTZ, The Catamaran™ Preferred Drug List is a MICARDIS/ HCT, TEKAMLO, TRIBENZOR, estradiol, estradiol/ norethindrone, estradiol transdermal system, estropipate, CENESTIN, COMBIPATCH, ENJUVIA, ESTRADERM, categories. The Preferred Drug List may not include al drugs covered by your prescription atorv
A Neurobehavioral Intervention and Assessment Program in Very Low BirthKaren Koldewijn, PT, Aleid van Wassenaer, MD, PhD, Marie-Jeanne Wolf, PhD, Dominique Meijssen, MSc,Bregje Houtzager, MSc, PhD, Anita Beelen, PhD, Joke Kok, MD, PhD, and Frans Nollet, MD, PhDObjective To determine whether the Infant Behavioral Assessment and Intervention Program (IBAIP) improvesdevelopment and behavior in ver