Material Safety Data Sheet
Creation Date 22-Dec-2009
Revision Date 22-Dec-2009
Revision Number 1

Product Name

Tetracycline hydrochloride


Achromycin Hydrochloride; Panmycin Hydrochloride.

Recommended Use

Emergency Telephone Number
Emergency Overview
Substances known to cause developmental toxicity in humans. Irritating to eyes. May cause skin and respiratory tract
Physical State Solid
odor No information available

Target Organs

Potential Health Effects
Acute Effects
Principle Routes of Exposure

May cause irritation. May be harmful in contact with skin. Inhalation
May cause irritation of respiratory tract. May be harmful if inhaled. Ingestion
May be harmful if swallowed. Ingestion may cause gastrointestinal irritation, nausea, vomiting and diarrhea.
Chronic Effects

Substances known to cause developmental toxicity in humans.
See Section 11 for additional Toxicological information.

Aggravated Medical Conditions

Preexisting eye disorders. Skin disorders.
Thermo Fisher Scientific - Tetracycline hydrochloride
Revision Date 22-Dec-2009
_____________________________________________________________________________________________ 3. COMPOSITION/INFORMATION ON INGREDIENTS


Eye Contact

Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Immediate medical attention is required.
Skin Contact

Wash off immediately with plenty of water for at least 15 minutes. Immediate medical attention is required.

Move to fresh air. Do not use mouth-to-mouth resuscitation if victim ingested or inhaled the substance; induce artificial respiration with a respiratory medical device.

Do not induce vomiting. Call a physician or Poison Control Center immediately.
Notes to Physician

Flash Point

Autoignition Temperature

Explosion Limits

Suitable Extinguishing Media

Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Unsuitable Extinguishing Media

Hazardous Combustion Products

Sensitivity to mechanical impact
Sensitivity to static discharge

Specific Hazards Arising from the Chemical
Keep product and empty container away from heat and sources of ignition

Protective Equipment and Precautions for Firefighters
As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective
gear. Thermal decomposition can lead to release of irritating gases and vapors.


Flammability 0
Instability 0
Physical hazards N/A

Thermo Fisher Scientific - Tetracycline hydrochloride
Revision Date 22-Dec-2009
_____________________________________________________________________________________________ Personal Precautions
Ensure adequate ventilation. Use personal protective equipment. Avoid dust formation.
Environmental Precautions

Should not be released into the environment.
Methods for Containment and Clean
Sweep up or vacuum up spillage and collect in suitable container for disposal. Avoid dust


Use only under a chemical fume hood. Wear personal protective equipment. Do not get in eyes, on skin, or on clothing. Avoid ingestion and inhalation. Store in freezer. Store under an inert atmosphere. Keep containers tightly closed in a cool, well-ventilated place. 8. EXPOSURE CONTROLS / PERSONAL PROTECTION
Engineering Measures

Use only under a chemical fume hood. Ensure that eyewash stations and safety showers are close to the workstation location.
Exposure Guidelines

This product does not contain any hazardous materials with occupational exposure limits established by the region specific regulatory bodies.

Immediately Dangerous to Life or Health

Personal Protective Equipment

Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin and body protection
Wear appropriate protective gloves and clothing to prevent skin exposure. Respiratory
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Physical State

Odor Threshold
Vapor Pressure
Vapor Density
Boiling Point/Range
Melting Point/Range
Decomposition temperature
Flash Point
Evaporation Rate
Specific Gravity
Molecular Weight
Molecular Formula

Thermo Fisher Scientific - Tetracycline hydrochloride
Revision Date 22-Dec-2009

Conditions to Avoid

Incompatible products. Excess heat. Avoid dust formation. Exposure to light. Exposure to moist air or water.
Incompatible Materials

Hazardous Decomposition Products

Carbon monoxide (CO), Carbon dioxide (CO2), Hydrogen chloride gas, Nitrogen oxides (NOx)
Hazardous Polymerization

Hazardous polymerization does not occur.
Hazardous Reactions .

Acute Toxicity

Component Information

LD50 Oral
LD50 Dermal
LC50 Inhalation


Toxicologically Synergistic


Chronic Toxicity

There are no known carcinogenic chemicals in this product

Mutagenic Effects

Reproductive Effects

Developmental Effects

Possible risk of harm to the unborn child.

Other Adverse Effects

See actual entry in RTECS for complete information. The toxicological properties have not been fully investigated.
Endocrine Disruptor Information

Thermo Fisher Scientific - Tetracycline hydrochloride
Revision Date 22-Dec-2009

Do not empty into drains.

Persistence and Degradability

Bioaccumulation/ Accumulation


Waste Disposal Methods

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. Chemical waste generators must also consult local, regional, and national hazardous waste regulations to ensure complete and accurate classification.

International Inventories


X - Listed
E - Indicates a substance that is the subject of a Section 5(e) Consent order under TSCA.
F - Indicates a substance that is the subject of a Section 5(f) Rule under TSCA.
N - Indicates a polymeric substance containing no free-radical initiator in its inventory name but is considered to cover the designated
polymer made with any free-radical initiator regardless of the amount used.

P - Indicates a commenced PMN substance
R - Indicates a substance that is the subject of a Section 6 risk management rule under TSCA.

Thermo Fisher Scientific - Tetracycline hydrochloride
Revision Date 22-Dec-2009
_____________________________________________________________________________________________ S - Indicates a substance that is identified in a proposed or final Significant New Use Rule
T - Indicates a substance that is the subject of a Section 4 test rule under TSCA.
XU - Indicates a substance exempt from reporting under the Inventory Update Rule, i.e. Partial Updating of the TSCA Inventory Data Base
Production and Site Reports (40 CFR 710(B).

Y1 - Indicates an exempt polymer that has a number-average molecular weight of 1,000 or greater.
Y2 - Indicates an exempt polymer that is a polyester and is made only from reactants included in a specified list of low concern reactants that
comprises one of the eligibility criteria for the exemption rule.

U.S. Federal Regulations

TSCA 12(b)
Not applicable

SARA 313

SARA 313 - Threshold
SARA 311/312 Hazardous Categorization

Acute Health Hazard
Chronic Health Hazard
Sudden Release of Pressure Hazard

Clean Water Act
Not applicable
Clean Air Act
Not applicable

Not applicable

Not Applicable

California Proposition 65
This product contains the following Proposition 65 chemicals:
California Prop. 65
Prop 65 NSRL

State Right-to-Know

New Jersey
Rhode Island
U.S. Department of Transportation
Reportable Quantity (RQ):

U.S. Department of Homeland Security
This product does not contain any DHS chemicals.

Thermo Fisher Scientific - Tetracycline hydrochloride
Revision Date 22-Dec-2009
_____________________________________________________________________________________________ Other International Regulations
Mexico - Grade

This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations (CPR) and the
MSDS contains all the information required by the CPR.
WHMIS Hazard Class
D2A Very toxic materials
D2B Toxic materials

Prepared By

Thermo Fisher ScientificTel: (412) 490-8929
Creation Date

Print Date

Revision Summary

"***", and red text indicates revision
The information provided on this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date
of its publication. The information given is designed only as a guide for safe handling, use, processing, storage,
transportation, disposal and release and is not to be considered as a warranty or quality specification. The information
relates only to the specific material designated and may not be valid for such material used in combination with any other
material or in any process, unless specified in the text.

End of MSDS


Source: http://www.westliberty.edu/health-and-safety/files/2013/04/Tetracycline-hydrochloride.pdf

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