Das pharmakologische Profil von Sildenafil zeigt neben der PDE5-Inhibition auch eine geringe Aktivität an der PDE6 in der Retina. Dies erklärt visuelle Nebenwirkungen wie Farbsehstörungen, die gelegentlich auftreten. Die orale Bioverfügbarkeit beträgt etwa 40 %, mit einer hohen Bindung an Plasmaproteine. Das Verteilungsvolumen ist groß, sodass die Substanz rasch in verschiedene Gewebe gelangt. Die Metabolisierung erfolgt hepatisch und produziert einen aktiven Metaboliten, der die pharmakologische Wirkung ergänzt. Nebenwirkungen sind dosisabhängig und umfassen Kopfschmerzen, Hautrötung und Dyspepsie. Bei Vergleichen innerhalb der Wirkstoffklasse wird viagra original regelmäßig als Beispiel für eine Substanz mit schneller, aber kurzzeitiger Wirkung aufgeführt.
Drug
MEDICATIONS & DOSAGES FOR HEDGEHOGS formulated by Caroline Gould & Tim Partridge B.V.Sc., M.R.C.V.S.
& used by Vale Wildlife Hospital & Rehabilitation Centre. BRAND NAME ACTIVE INGREDIENT
Dose rate: 75mg/kg bodyweight daily for 7 days. Therefore:
250mg/ml injectable = 0.3mls/kg daily i/m or s/c, 50mg tablets = one & a half tablets/kg daily oral y, 125mg tablets = five eighths tablet/kg daily (closest calc. poss). ANTIROBE
Dose rate: 25mg/kg bodyweight daily for at least 7 days. Therefore:
25mg capsules = 1 capsule daily.
Dose rate: 75mg/kg oral y once, then repeat after 10 days
Coccidiosis treatment = 2ml/kg orally
Dose rate: 20mg/kg twice daily for at least 7 days. Therefore:
Antibiotic - injectable & oral preparations
2.5% Baytril = 0.8mls/kg twice daily (i/m or s/c if inj or), Recommended antibiotic with worming treatments 5% Baytril = 0.4mls/kg twice daily (i/m or s/c if inj.) BISOLVON 3mgs/ml injection = 1ml/kg daily i/m or s/c for 7-10 days, Use with treatments for heavy 10mg/gm powder = 0.3gms/kg daily oral y for 7-10 days. Crenosoma (lungworm) burdens
Dose rate: 30mg/kg daily for 7 days. Therefore:
180mg/ml injectable = 0.2ml/kg daily i/m or s/c (closest calc), 50mg tablets = half a tablet/kg daily oral y (closest calc), 100mg oral syrup = 0.3ml/kg. CLAMOXYL LA
0.7mls/kg bodyweight i/m or s/c every other day. Inflammation: 1mg/kg = 0.5ml/kg, DEXADRESON Shock: 5mg/kg (2.5ml/kg), Head or spinal trauma: 5mg/kg initial y (2.5ml/kg), then 2mg/kg (1ml/kg) s/c twice a day.
1-3mg/kg every 6-8 hours acc to degree of sedation required.
DIAZEPAM, 5mg/ml injection = 0.2 – 0.6mls/kg i/m or i/v, 5mg tablets = one quarter to one half tablet/kg oral y.
Dose rate: 5-10mg/kg twice daily. Therefore:
50mg/ml injectable = 0.1-0.2ml/kg twice daily i/m, s/c or i/v, 20mg tablets = one quarter to half a tablet/kg twice daily oral y.
Dose rate: 50mg/kg twice daily for 7 days. Therefore:
ENGEMYCIN 50mg/ml injectable = 1ml/kg twice dailyi/m or s/c for 7 days, 50mg tablets = 1 tablet/kg twice daily oral y for 7 days, 100mg tablets = half a tablet/kg twice daily oral y for 7 days.
Dose rate: 40mg/kg daily for 5-10 days. Therefore:
5mg/ml injectable = 8mls/kg daily s/c or i/v for 5-10 days, METRONIDAZOLE 200mg tablets = one fifth of a tablet/kg daily oral y for 5-10 days, 40mg oral solution = 1ml/kg daily for 5-10 days. Profender Spot-on (cat) = 0.5mls/kg on skin
3 doses (occ. 4 doses nec.), each 7 days apart or,
TREATMENT Flukiver Oral Suspension = 3ml/kg, mix in v.smal amount food,
repeat in 2 weeks. DO NOT USE FOR HOGS UNDER 300gms
Mix 1:50 with water e.g. 5mls Imaverol to 250mls water (or 1ml
IMAVEROL
Spray wel & al ow to ‘drip dry’. Spray every 3 days until the hog
has had 4 sprays. Keep in warm during treatment.
Smal handheld houseplant sprayers are ideal for this. ITRAFUNGOL
0.4ml/kg - 3 inj, s/c each 1 week apart. Use if Capillaria eggs found in faecal sample Mites: 1-3 drops dep. on size directly onto skin on back of neck.
Dose rate: 4mg/ kg = 0.4mls/kg daily i/m, s/c or i/v for up to 3 days. DO NOT USE IF CORTICOSTEROID GIVEN LEVACIDE
Dose rate: 27mgs/kg = 0.35mls/kg daily s/c for 3 days. Use if Crenosoma larvae found in faecal sample MARBOCYLSA,
Dose rate: 8mgs/kg daily for at least 7 days. Therefore:
SA 1% = 0.8ml/kg daily s/c for at least 7 days, MARBOCYL 2% Recommended antibiotic with worming treatments 2% injectable = 0.4ml/kg daily s/c for at least 7 days.
Dose rate: 0.5mg/kg for up to 3 days. Therefore:
5mgs/ml injection = 0.1mls/kg daily s/c for up to 3 days, 0.5mg/ml oral = 1ml/kg daily for up to 3 days, 1.5mg/ml oral = 0.35ml/kg daily for up to 3 days.
Dose rate: 50mg/kg twice daily. Therefore:
MILLOPHYLLINE 140mg/ml injectable = 0.35mls/kg twice daily i/m or s/c, 100mg tablets = half a tablet/kg twice daily oral y, 200mg tablets = a quarter of a tablet/kg twice daily oral y.
Dose rate: 5mg/kg daily for up to 3 days. Therefore:
RIMADYL,
Non-steroidal analgesic / anti-inflammatory
50mgs/ml injection = 0.1mls/kg daily i/m, s/c or i/v, NOROCARP 20mg tablets = quarter of a tablet/kg daily oral y. DO NOT USE IF CORTICOSTEROID GIVEN
Dose rate: 100mg/kg daily for at least 7 days. Therefore:
175mg/ml injectable = 0.7mls/kg daily i/m or s/c for 7 days, 50mg tablets = 2 tablets/kg daily for 7 days oral y, Palatable drops = 2mls/kg daily for 7 days oral y. MEDICATIONS & DOSAGES FOR HEDGEHOGS formulated by Caroline Gould & Tim Partridge B.V.Sc., M.R.C.V.S.
& used by Vale Wildlife Hospital & Rehabilitation Centre.
100mg/kg oral y daily for 5 days. Repeat after 10 days. Note: Levacide inj more effective Telmin granules = 1g/kg daily oral y, Telmin 200mg/g paste = 0.5ml/kg daily oral y. TORBUGESIC
0.5mgs/kg = 0.05ml/kg 4 times daily i/m or s/c
TRIBRISSEN 24% injection = 0.5mls/kg daily s/c, TYLAN 200
Dose rate: 20mg/kg daily for 7 days. 200mg injectable = 0.1ml/kg daily i/m or s/c. VETERGESIC
0.1-0.15mls/kg every 6 - 12 hours i/m or s/c. CAN BE GIVEN IF CORTICOSTEROID GIVEN
Dose rate:3.5mg/kg twice daily for at least 14 days. Therefore: 25mg/ml injectable = 0.15ml/kg twice daily s/c, 15mg syrup = 0.25ml/kg twice daily oral y. i/m = intramuscular s/c = subcutaneous i/v = intravenous Oral preparations can often be mixed with a small amount of food. If you need any advice on any of the medications or doses for hedgehogs please contact Caroline on 01386 882288 or email [email protected]
Arie e Ruoli del Seicento/Settecento Belinda, prima e seconda strega, seconda donna, marinaio e spirito Didone ed Enea (1689) H. Purcell Serpina La Serva Padrona (1733) G.B. Pergolesi Lisetta Quando si trovano, le basse femmine (da Il mondo della luna - 1750) B. Galuppi Lesbina Il Filosofo di campagna (1754) B. Galuppi Cecchina La cecchina, ossia la buona figliola (1760) N. P
Health-related quality of life changes among users of depotmedroxyprogesterone acetate for contraception☆,☆☆Sikolia Z. Wanyonyi⁎, William R. Stones, Evan SequeiraDepartment of Obstetrics and Gynaecology, Aga Khan University Hospital, Nairobi; 3rd Parklands Avenue, Box 30270, Nairobi 00100, KenyaReceived 27 March 2011; revised 27 May 2011; accepted 28 May 2011Background: Depot medr