Das pharmakologische Profil von Sildenafil zeigt neben der PDE5-Inhibition auch eine geringe Aktivität an der PDE6 in der Retina. Dies erklärt visuelle Nebenwirkungen wie Farbsehstörungen, die gelegentlich auftreten. Die orale Bioverfügbarkeit beträgt etwa 40 %, mit einer hohen Bindung an Plasmaproteine. Das Verteilungsvolumen ist groß, sodass die Substanz rasch in verschiedene Gewebe gelangt. Die Metabolisierung erfolgt hepatisch und produziert einen aktiven Metaboliten, der die pharmakologische Wirkung ergänzt. Nebenwirkungen sind dosisabhängig und umfassen Kopfschmerzen, Hautrötung und Dyspepsie. Bei Vergleichen innerhalb der Wirkstoffklasse wird viagra original regelmäßig als Beispiel für eine Substanz mit schneller, aber kurzzeitiger Wirkung aufgeführt.

Http://www.clubsonline.com.au/uploads/swimresults/victoria/agec

Melbourne Sports & Aquatic Center - Site License
2011 Victorian Age Championships - 17/12/2010 to 22/12/2010
Event 177 Girls 12 Years 400 LC Metre IM
==================================================================
Name Age Team Seed Finals
==================================================================
1 Stickland, Lushavel 12 FOOTSCRAY 5:25.23 5:18.32
34.51 1:15.18 (40.67)
1:55.76 (40.58) 2:35.27 (39.51)
3:21.67 (46.40) 4:08.13 (46.46)
4:43.26 (35.13) 5:18.32 (35.06)
2 Schendelaar-Kemp, Pai 12 HPKCO-CO 5:27.54 5:19.60
30.80 1:08.46 (37.66)
1:50.41 (41.95) 2:30.88 (40.47)
3:18.98 (48.10) 4:06.88 (47.90)
4:44.21 (37.33) 5:19.60 (35.39)
3 Good, Alexandra 12 SYP 5:28.61 5:20.47
34.00 1:13.23 (39.23)
1:53.74 (40.51) 2:32.71 (38.97)
3:20.82 (48.11) 4:09.99 (49.17)
4:44.93 (34.94) 5:20.47 (35.54)
4 Allen, Leah 12 SWIMLAND 5:32.67 5:27.81
33.67 1:14.86 (41.19)
1:57.10 (42.24) 2:38.04 (40.94)
3:25.83 (47.79) 4:13.56 (47.73)
4:50.59 (37.03) 5:27.81 (37.22)
5 Smith, Mikayla 12 NUNAWADING SWIMM 5:32.73 5:30.64
34.94 1:16.65 (41.71)
2:02.32 (45.67)
3:30.66 ( ) 4:16.09 (45.43)
4:54.14 (38.05) 5:30.64 (36.50)
Event 177 Girls 13 Years 400 LC Metre IM
==================================================================
Name Age Team Seed Finals
==================================================================
1 Pircher, Karlene 13 MELBOURNE VICENT 5:04.16 5:05.31
32.97 1:10.96 (37.99)
1:50.94 (39.98) 2:30.04 (39.10)
3:11.60 (41.56) 3:53.09 (41.49)
4:29.63 (36.54) 5:05.31 (35.68)
2 Schlicht, Jemma 13 MLC AQUATIC, VIC 5:24.65 5:10.11
31.04 1:08.12 (37.08)
1:50.05 (41.93) 2:30.86 (40.81)
3:16.86 (46.00) 4:03.24 (46.38)
4:37.76 (34.52) 5:10.11 (32.35)
3 Tsebelis, Georgia 13 TRARALGON 5:14.87 5:13.17
32.17 1:10.35 (38.18)
1:49.46 (39.11) 2:28.68 (39.22)
3:15.17 (46.49) 4:02.56 (47.39)
4:37.47 (34.91) 5:13.17 (35.70)
4 Whittaker, Sian 13 CA TRITONS 5:20.79 5:14.49
33.30 1:12.64 (39.34)
1:52.51 (39.87) 2:30.22 (37.71)
3:17.20 (46.98) 4:03.84 (46.64)
4:40.15 (36.31) 5:14.49 (34.34)
5 Camenzuli, Emily 13 MARIBYRNONG SWIM 5:20.11 5:14.83
32.82 1:11.10 (38.28)
http://www.clubsonline.com.au/uploads/swimresults/Victoria/AgeChamps/101217F1.
1:53.69 (42.59) 2:34.55 (40.86) 3:20.33 (45.78) 4:05.86 (45.53) 4:41.48 (35.62) 5:14.83 (33.35) 6 Scalone, Kirsten 13 NTH-WEST AQUATIC 5:30.32 5:30.04 33.84 1:16.03 (42.19) 1:56.85 (40.82) 2:37.08 (40.23) 3:26.29 (49.21) 4:16.10 (49.81) 4:54.22 (38.12) 5:30.04 (35.82) 7 Fahour, Yasmin 13 MLC AQUATIC, VIC 5:33.52 5:34.31 33.80 1:15.12 (41.32) 1:58.91 (43.79) 2:40.78 (41.87) 3:28.48 (47.70) 4:17.88 (49.40) 4:56.28 (38.40) 5:34.31 (38.03) http://www.clubsonline.com.au/uploads/swimresults/Victoria/AgeChamps/101217F1.

Source: http://www.swimnz.co.nz/meet_results/files/VictorianAgeChampionships22122010/Event%20177-t.pdf

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