Microsoft word - pr december 2008 1.doc

SILVER SPRING, MD 20905-5726

CoMeD President [Rev. Lisa K. Sykes (Richmond, VA) 804-364-8426] CoMeD Sci. Advisor [Dr. King (Lake Hiawatha, NJ) 973-263-4843] WASHINGTON, DC – In April of 2008, the American College of Medical Genetics (ACMG), an
AMA-recognized board, issued clinical practice guidelines that clinical geneticists should follow
in determining the etiology for those with an autistic spectrum disorder (ASD) diagnosis and in
treating patients with this diagnosis. This study, “Autism spectrum disorder-associated
biomarkers for case evaluation and management by clinical geneticists” in Expert Review of
Molecular Diagnostics
,[ 1 ] confirms that there are now well-established, routine, clinically
available, identified biomarkers to help clinical geneticists medically evaluate and treat
individuals diagnosed with an ASD and briefly outlines some recognized biomarkers. Depending
on the cause of the ASD, these researchers have found that “associated medical risks may be
identified, which may lead to screening and potential morbidity prevention in patients and other
family members.” The non-profit CoMeD, Inc., and, through a grant from the Brenen Hornstein
Autism Research & Education (BHARE) Foundation
, the non-profit Institute of Chronic Illnesses,
Inc. funded this research study.
The important clinical tools identified for medical evaluation and treatment response monitoring
‰ Pophyrin biomarkers to help determine if mercury toxicity is present, and, when it is
found, to monitor changes in mercury-burden during detoxification therapies. ‰ Trans-Sulfuration biomarkers to help determine if mercury biochemical susceptibility
is present and, when it is found, to monitor patient response during supplementation with nutritional therapies such as methylcobalamin (the methyl form of vitamin B12), folinic acid, and pyroxidine (vitamin B6). ‰ Oxidative Stress/Inflammation biomarkers – to help determine if there are excessive by-
products of metabolic pathways, and, when they are found, to monitor patient progress during supplementation with anti-inflammatory drugs such as Aldactone® (spironolactone). ‰ Hormonal biomarkers – to help determine if hormonal abnormalities are present and,
when they are found, to monitor patient progress during the indicated treatment with hormonal regulation drugs such as Lupron® (leuprolide acetate) and Yaz® (drospirenone/ethynyl estradiol). ‰ Mitochondrial Dysfunction biomarkers – to help determine if there are disruptions in the
energy production pathways, and, when they are found, to monitor patient progress during supplementation with drugs such as Carnitor® (L-carnitine). ‰ Genetic biomarkers – to help determine if there are genetic causal or susceptibility factors
present, and, when they are found, to provide insights into behavior modification to help reduce the impact of such genetic factors.
[1] Geier Da, Geier MR. Expert. Rev. Mol. Diagn. 2008; 8(6): 671-674.
Today, any parent, physician, or healthcare provider can easily engage the services of a clinical geneticist who is following the ACMG practice guidelines to help evaluate and treat those diagnosed with an ASD by contacting ASD Clinics, LLC, a national outreach clinic helping to provide clinical genetic services through the Genetic Centers of America. For information about scheduling a consultation, please call (301) 989-0548. West Coast - Genetic Consultants of Washington State (Seattle, WA) Central – Genetic Consultants of Indiana (Indianapolis, IN) East Coast – Genetic Consultants of Maryland (Washington, DC) Your generous tax-free donations will help us to fund additional research, similar to the present study, to examine the biomedical basis and treatments for patients diagnosed with an ASD. To support the ongoing efforts of CoMeD, Inc. with your tax-deductible contributions, please use the PayPal link on CoMeD’s Internet website, CoMeD, Inc. is a not-for-profit 501(c)(3) corporation that is actively engaged in legal, educational and scientific efforts to stop all use of mercury in medicine, and to ban the use of all mercury-containing


Rt sept 2003

A newsletter from Alcoholics Anonymous San Fernando Valley Central Office What is AA? AA is a spirit. It cannot be touched, nor can it be completelyunderstood. It is as wide as the world, yet small enough to fitsnugly into the hearts of women and men. It has brought light whereonly darkness dwelt. It has given hope to the hopeless and help to *Upcoming those who yearned in despair. It has

M. K. JUCHHEIM GmbH & Co JUMO Instrument Co. Ltd. JUMO PROCESS CONTROL INC. Data Sheet 90.9722 Terminal heads and blocks ■ for thermocouples and resistance thermometers ■ terminal heads in different materials ■ Protection IP65 max. ■ versions for lead sealing Terminal heads (pages 1 to 4) DIN 43 729 specifies the terminal head forms A and B, which differ

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