Thames Valley Y-Site Intravenous Drugs Compatibility Chart (November 2005)
Prepared by the Thames Valley Critical Care Network Pharmacists Group*
Note: This table can be used for Y-site compatibility at the usual manufacturers concentrations. You should also ensure that the drugs checked are compatible in terms of carrier fluid This table gives information for two drug combinations only . It can not be extrapolated to three drug combinations Use of higher than the manufacturers recommended concentrations (eg in fluid restriction) may affect compatibility The majority of sources cited define compatibility by physical compatibility rather than chemical compatibility This table is a guide only. Full information can be obtained from your pharmacy department Acetylcysteine References Adrenaline 9 Adrenaline 1 Compatible (Reference 1)
1 "Pocket Guide to Injectable Drugs" 11th Edition, Lawrence Trissel, 2001.
Alfentanil 9 Alfentanil
American Society of Health System Pharmacists (ISBN 1-58528-023-2)
Aminophylline 9 Aminophylline
2 "King Guide to Parenteral Admixtures: Compatibility of Critical Care Admixtures 2005",
Amiodarone 9 Amiodarone
Patrick Catania, 2005. School of Pharmacy, University of the Pacific (www.kingguide.com)
Aprotinin 9 Aprotinin Atracurium 9 Atracurium
4 Parvolex Injection, ABPI Medicines Compendium 2005, p1840-1841 (ISBN 0-0907102-23-9)
Calcium Chloride Calcium Chloride
5 Rapifen Intensive Care, ABPI Medicines Compendium 2005, p2024-2025 (ISBN 0-0907102-23-9)
Calcium Gluconate Calcium Gluconate
6 Cordarone X Intravenous, ABPI Medicines Compendium 2005, p547-548 (ISBN 0-0907102-23-9)
Ciprofloxacin Ciprofloxacin
7 Tracrium Injection, ABPI Medicines Compendium 2005, p2417-2418 (ISBN 0-0907102-23-9)
Cisatracurium Cisatracurium
8 Nimbex Forte Injection, Nimbex Injection 2mg/ml , ABPI Medicines Compendium 2005, p1699-1703 (ISBN 0-0907102-23-9)
Clonidine 9 Clonidine
9 Catapress Ampoules, ABPI Medicines Compendium 2005, p411-412 (ISBN 0-0907102-23-9)
Compound Sodium Lactate Solution (Hartmann's) Compound Sodium Lactate Solution (Hartmann's)
10 Dopacard, ABPI Medicines Compendium 2005, p721 (ISBN 0-0907102-23-9)
Disodium Hydrogen Phosphate Disodium Hydrogen Phosphate
11 Xigris, ABPI Medicines Compendium 2005, p2655-2657 (ISBN 0-0907102-23-9)
Dobutamine 9 Dobutamine
12 Ventolin Injection, ABPI Medicines Compendium 2005, p2537-2538 (ISBN 0-0907102-23-9)
Dopamine 9 Dopamine
13 Flagyl Injection (100ml), ABPI Medicines Compendium 2005, p935-936 (ISBN 0-0907102-23-9)
Dopexamine 9 Dopexamine
14 Losec IV Infusion, ABPI Medicines Compendium 2005, p1403-1404 (ISBN 0-0907102-23-9)
Drotrecogin Alfa (Activated) Drotrecogin Alfa (Activated)
15 Diprivan 1%, Diprivan 2%, ABPI Medicines Compendium 2005, p697-701 (ISBN 0-0907102-23-9)
Esmolol 9
16 Ultiva Injection, ABPI Medicines Compendium 2005, p2483-2487 (ISBN 0-0907102-23-9)
Fentanyl 9 Fentanyl
17 "Physical and chemical compatibility of drotrecogin alfa (activated) with 34 drugs during simulated Y-site administration"
Furosemide 9 Furosemide
HY Mann, SL Demmon, DA Boelk et al, Am J Health-Syst Pharm 2004; 61: 2664-2671
Gentamicin Gentamicin
18 "John Farman intensive care unit compatibility chart", Cambridge University Hospitals NHS Foundation Trust,
Glucose 4%, Sodium Chloride 0.18% Glucose 4%, Sodium Chloride 0.18%
Pharmacy Department, In-house data generated by Brit Cadman and Tim House
Glucose 5% 9 Glucose 5%
19 AstraZeneca, Personal communication (16/03/2005)
Glyceryl Trinitrate (GTN) 2 Glyceryl Trinitrate (GTN)
20 Bayer, Personal communication (16/03/2005)
Heparin (Sodium) 9 Heparin (Sodium)
21 Zeneus Pharma, Personal communication (22/03/2005)
Insulin (Soluble) 9 Insulin (Soluble)
22 "Handbook on injectible drugs" 13th Edition, LA Trissel, 2005. Isosorbide Dinitrate 9 Isosorbide Dinitrate
American Society of Health System Pharmacists (ISBN 1-58528-107-7)
Labetalol 9 Labetalol
23 Schwartz Pharma, Personal communication (22/03/2005)
Magnesium Sulphate Magnesium Sulphate
24 Akzo Nobel, Personal communication (16/03/2005)
Mannitol Mannitol Metronidazole Metronidazole Midazolam 9 Midazolam Milrinone Milrinone Morphine 9 Morphine Noradrenaline 9 Noradrenaline Omeprazole 9 Omeprazole Potassium Chloridev Potassium Chloride Potassium Phosphate Potassium Phosphate Propofol Propofol Remifentanil 9 Remifentanil Rocuronium 9 Rocuronium Salbutamol Salbutamol Sodium Bicarbonate Sodium Bicarbonate Sodium Chloride 0.9% 9 Sodium Chloride 0.9% Sodium Nitroprusside 2 Sodium Nitroprusside Thiopental Thiopental Vancomycin Vancomycin Vasopressin (Arginine Vasopressin) Vasopressin (Arginine Vasopressin) Vecuronium 9 Vecuronium *Thames Valley Critical Care Network Pharmacists Group
John Radcliffe Hospital, Dep. Chief P'cists Rep
John Radcliffe Hospital, (AICU), Chair (16/01/2004)
John Radcliffe Hospital, Chief Pharmacists Rep
Secretarial support was provided by Sue Gurney
Data Input By: Sue Gurney, Mark Borthwick
2005, Thames Valley Critical Care Network Pharmacists Group
Chart Approved By: Thames Valley Critical Care Network Pharmacists Group, 10 November 2005
PRESS RELEASE NEW DATA FROM PHASE 3 STUDIES PROVIDE ADDITIONAL EVIDENCE SUPPORTING TREATMENT EFFECT FOR ORAL BG-12 (DIMETHYL FUMARATE) IN MULTIPLE SCLEROSIS – Interim Results from ENDORSE Extension Study Further Support Safety Profile from Weston, Mass. – October 12, 2012 – Today Biogen Idec (NASDAQ: BIIB) announced new data from studies evaluating oral BG-12 (dim
A Excelentísimo Señor Embajador Mag. Gabriel Kramarics Botschafter der österreichischen Botschaft in Guatemala 6a Avenida 20 – 25, Zona 10 Edificio Plaza Maritima, local 4-1, 01010 Guatemala Ciudad Guatemala Y Señor Philippe Combescot Encargado de Negocios a.i. Delegación de la Comisión Europea en Guatemala 14 calle 3-51 Zona 10 Edificio Muarano Center Nivel 14 Ciudad de Guatemala Guatemal