Das pharmakologische Profil von Sildenafil zeigt neben der PDE5-Inhibition auch eine geringe Aktivität an der PDE6 in der Retina. Dies erklärt visuelle Nebenwirkungen wie Farbsehstörungen, die gelegentlich auftreten. Die orale Bioverfügbarkeit beträgt etwa 40 %, mit einer hohen Bindung an Plasmaproteine. Das Verteilungsvolumen ist groß, sodass die Substanz rasch in verschiedene Gewebe gelangt. Die Metabolisierung erfolgt hepatisch und produziert einen aktiven Metaboliten, der die pharmakologische Wirkung ergänzt. Nebenwirkungen sind dosisabhängig und umfassen Kopfschmerzen, Hautrötung und Dyspepsie. Bei Vergleichen innerhalb der Wirkstoffklasse wird viagra original regelmäßig als Beispiel für eine Substanz mit schneller, aber kurzzeitiger Wirkung aufgeführt.
Broadreachrx.com
Broadreach ANTI-INFECTIVE AGENTS (ORAL) OTHER ANTI-INFECTIVES ANTIPARKINSON ARKINSON AGENTS CARDIOVASCULAR ANTIBIOTICS, CEPHALOSPORINS MEDICATIONS ACE INHIBITORS Erythromycins & Other Macrolides
Clarithromycin (generic Biaxin, Biaxin XL)
TOPICAL ANTIBACTERIAL DRUGS ANTIPSYCHOTICS ALPHA BLOCKERS
Erythromycin Base (generic Ery-Tab, E-Mycin)
Erythromycin Ethylsuccinate (generic E.E.S.,
TOPICAL ANTIFUNGAL AGENTS
Erythromycin Stearate (generic Erythrocin)
ANTIARRHYTHMICS Penicillins AUTONOMIC and CENTRAL CENTRAL NERVOUS SYSTEM AGENTS
Amoxicillin/ Pot. Clav. (generic Augmentin)
ANALGESICS, ANTIMIGRAINAL ANXIOLYTICS, SEDATIVES AND HYPNOTICS BETA-ADRENERGIC ANTAGONIST Quinolones ANTIVERTIGO/ANTIEMETICS Sulfonamides Tetracyclines
Doxycycline (generic Vibramycin, Monodox)
ANALGESICS, NARCOTIC
Sotalol (generic Betapace)Timolol (generic Blocadren)
ANTIFUNGAL AGENTS
APAP/ Codeine (generic Tylenol w/ Codeine)
STIMULANTS/ DRUGS
APAP/ Hydrocodone (generic Vicodin/ Norco)
TO TREAT ATTENTION DEFICIT DISORDER CALCIUM CHANNEL BLOCKERS
ASA/ Codeine (generic Empirin w/ Codeine)
Butabital/ Acetaminophen/ Caffeine (generic
Griseofulvin (generic Gris-PEG/ Grifulvin)
Methylphenidate (generic Ritalin/ Methylin)
Hydrocodone/ Ibuprofen (generic Vicoprofen)
DRUGS TO PREVENT AND TREAT GOUT CARDIAC GLYCOSIDES
Meperidine/ Promethazine (generic Mepergan)
CHOLESTEROL-LOWERING ANTIFUNGAL (VAGINAL) MUSCLE RELAXANTS/ ANTISPASMODICS ANALGESICS, NON-STEROIDAL ANTIHELMINICS ANTI-INFLAMMATORY ANTI-INFECTIVE AGENTS-
Caffeine (generic Soma Compound with Codeine)
SPECIALIZED INDICATIONS
&KORU]R[D]RQH JHQHULF3DUDIRQ)RUWH'6&
DIURETICS
&\FOREHQ]DSULQH+&/ JHQHULF)OH[HULO
PSYCHOTHERAPEUTIC AGENTS
Hydrochlorothiazide Indapamide (generic Lozol)
ANTINEOPLASTIC/ ANTIDEPRESSANTS IMMUNOSUPPRESANTS ANTICONVULSANTS
Amitriptyline/ Perphenazine (generic Triavil)
Bupropion (generic Wellbutrin Wellbutrin SR,
Phenytoin/ Phenytoin Extended (genericDilantin)
70% of Generics
Valproic Acid/ Valproate Sodium (generic
are $10 or less ANTI-TUBERCULAR AGENT
Divalproex Sodium (generic Depakote, Sprinkle,
Brand Member Responsibility ANTIVIRAL AGENTS from $20.00 to $75.00 most average $35.00
Nortriptyline (generic Pamelor)Paroxetine (generic Paxil)Sertraline (generic Zoloft)Trazadone (generic Desyrel)
For a complete formulary vist our website at www.BroadreachRx.com or call 1-866-718-2375 DIURETIC COMBINATIONS DRUGS AFFECTING THE OPHTHALMIC AGENTS BETA AGONIST INHALERS THROAT AND MOUTH GLAUCOMA AGENTS Inhaled Corticosteroids ENDOCRINE MEDICATIONS Intranasal Steroids CORTICOSTEROID DRUGS OPHTHALMIC MOST PRESCRIPTION ONLY ANTI-INFECTIVES/ GENERICS IN THE FOLLOWING CORTICOSTEROID DRUGS CATEGORIES ARE COVERED EXPECTORANT COMBINATIONS DECONGESTANTS/ANTIHISTAMINES ANTI-TUSSIVE COMBINATIONS RESPIRATORY, ALLERGY, ANTIDIABETIC AGENTS COUGH & COLD PRENATAL VITAMINS ANTIHYPERTENSIVES Brand Formulary Therapeutic Brand Category THYROID AND Name ANTI-THYROID DRUGS OTHER CARDIOVASCULAR
Levothyroxine (generic Synthroid/ Levoxyl)
OPHTHALMIC DRUGS VASODILATING DRUGS
Atropine Sulfate (generic Isopto Atropine)
GASTROINTESTINAL MEDICATIONS
1DSKD]ROLQH JHQHULF$.&RQ/LTXL¿OP
ANTISPASMODICS DERMATOLOGICALS ANTI-ACNE OPHTHALMIC TOPICAL ANTIBACTERIAL DRUGS ANTIPSORIASIS OPHTHALMIC TOPICAL ANTIVIRAL DRUGS OTHER DERMATOLOGICAL DRUGS GASTROINTESTINAL OBSTETRICAL AND CORTICOSTEROIDS GYNECOLOGICAL MEDICATIONS ANDROGENS CONTRACEPTIVES
Ethinyl Estradiol and Desogestrel (generic
Ethinyl Estradiol and Ethynodiol Diacetate
Ethinyl Estradiol and Levonorgesterel (generic
PROTON PUMP INHIBITORS MISCELLANEOUS UROLOGICALS
Norethindrone/ Ethinyl Estradiol (generic
Norethindrone/ EthinylEstradiol (generic
NUTRITION, BLOOD MODIFIERS, ELECTROLYTES DRUGS AND VITAMINS EAR, NOSE, AND THROAT MEDICA- AFFECTING COAGULATION TIONS DRUGS AFFECTING THE EAR
Norgestimate/ Ethinyl Estradiol (generic Ortho
Antipyrine/Benzocaine (generic Auralgan/
FLUORIDE PRODUCTS ORAL ESTROGEN DRUGS POTASSIUM SUPPLEMENTS
Potassium Chloride (generic K-DUR/ Micro-K)
PROGESTIN DRUGS VITAMINS/ MINERALS PULMONARY and ASTHMA
of specific diagnostic criteria based on an independent RESEARCH LETTER review of the semistructured history, detailed mental sta-tus examination, and complete neurological examina-tion. These patients and their legal representatives par- Longitudinal Cortical Atrophy ticipated in an informed consent procedure approved bythe institutional review board at the University of Penn- in Amyot
C l u st e r o f i m p o rt e d m a l a r i a f r o m G a m b i a i n f i n l a n d – t r av e l l e r s d o n ot l i st e n to G i v e n a dv i C eK Valve ([email protected])1, E Ruotsalainen1, T Kärki1, E Pekkanen1, H Siikamäki21. National Public Health Institute, Department of Infectious Disease Epidemiology and Control, Helsinki, Finland2. Helsinki University Central Hospital, Division
Broadreach