Cv: réjan vigot

Réjan Vigot
Work addressLauney Research Unit for Molecular NeurocyberneticsRIKEN – Brain Science InstituteHirosawa 2-1, Wako, Saitama 351-0198, JapanTel.: +81(0)48-462-1111 (ext. 7488) Fax: +81(0)48-467-5485E-mail : [email protected] Present position2009- Researcher, Launey Research Unit, RIKEN – BSI, Japan University Degrees1996 Ph. D. in Neurosciences, University of Paris XI, Orsay, France1990 Master degree in Animal Physiology, University of Paris XI, Orsay, France Professional experience2007-2009: Researcher at the Okinawa Institute of Science and Technology, Unit for Molecular Neurobiology of Learning & Memory (Dr. S. Endo) Electrophysiological study of learning and memory in ICER-deficient and ICER-overexpressing mice 2003-2006: Postdoctoral fellow at the University of Basel, Department of Physiology (Prof. B. Bettler) Electrophysiological study of GABA(B) receptors 1997-2002: Japan Society for the Promotion of Science postdoctoral fellow (2 years) and postdoctoral fellow (3 years) at the National Institute for Basic Biology, Division of Speciation Mechanisms I (Prof. T. Yamamori), Okazaki, Japan. In vivo and in vitro studies of the cerebellar long-term depression. 1994-1995 : Assistant in neurosurgery, Hôpital Necker-Enfants Malades (Prof. A.-P. Kahn), Paris, France.
1991-1996 : Diploma and Thesis at the Laboratoire de Physiologie de la Motricité – CNRS (Dr C. Batini), University Pierre et Marie Curie, Paris VI, CHU Pitié-Salpêtrière, Paris, France. GABA(A) and GABA(B) receptors in intact and chronically deafferented cerebellum: pharmacological and electrophysiological study. - Casanova E., Guetg N., Vigot R., Seddik R., Julio-Pieper M., Hyland N.P., Cryan J.F.,
Gassmann M. and Bettler B. A Mouse Model for Visualization of GABAB Receptors. Genesis, 2009, 00, 1-8.
- Guetg N.*, Seddik R.*, Vigot R., Turecek R., Gassmann M., Vogt K.E., Bräuner-Osborne
H., Shigemoto R., Kretz O., Frotscher M., Kulik A. and Bettler B. The GABAB1a Isoform Mediates Heterosynaptic Depression at Hippocampal Mossy Fiber Synapses. The Journal of Neuroscience, 2009, 106(11): 4459-64.
- Vigot R.*, Barbieri S.*, Bräuner-Osborne H.*, Turecek R., Shigemoto R., Zhang Y.-P.,
Luján R., Jacobson L.H., Biermann B., Fritschy J.-M., Vacher C.-M., Müller M., Sansig G. , Cryan J.F., Kaupmann K., Gassmann M., Oertner T. G., Bettler B. Differential compartmentalization and distinct functions of GABAB receptor variants. Neuron, 2006, 50(4): 589-601.
- Haller C., Casanova E., Muller M., Vacher C.-M., Vigot R., Doll T., Barbieri S., Gassmann
M. and Bettler B. Floxed allele for conditional inactivation of the GABAB(1) gene. Genesis, 2004, 40(3):125-30.
- Gassmann M.*, Shaban H.*, Vigot R.*, Sansig G., Haller C., Barbieri S., Humeau Y.,
Schuler V., Müller M., Kinzel B., Klebs K., Schmutz M., Froestl W., Heid J., Kelly
P.H., Gentry C., Jaton A-L., Van der Putten H., Mombereau C., Lecourtier L.,
Mosbacher J., Cryan J.F., Fritschy J-M., Lüthi A., Kaupmann K. and Bettler B.
Redistribution of GABAB(1) protein and atypical GABAB responses in GABAB(2)-
deficient mice. The Journal of Neuroscience, 2004, 24(27):6086-97
*: These authors contributed equally to this study.
- Vigot R., Kado R.T. and Batini C. Increased Calbindin-D28k immunoreactivity in rat
cerebellar Purkinje cell with excitatory amino acids agonists is not dependent on protein synthesis. Archives Italiennes de Biologie, 2004, 142(1):69-75.
- Vigot R. Cerebellar long-term depression: a mechanism for learning and memory.
Médecine/Sciences, 2003, 19, 437-441.
- Vigot R., Batini C., Kado R.T. and Yamamori T. Synaptic LTD in vivo recorded on the rat
cerebellar cortex. Archives Italiennes de Biologie, 2002, 140, 1-12.
- Karachot L., Shirai Y., Vigot R., Yamamori T. and Ito M. Induction of long-term depression
in cerebellar Purkinje cells requires a rapidly turned over protein. Journal of Neurophysiology, 2001, 86(1), 280-289.
- Karachot L., Shirai Y., Vigot R., Yamamori T. and Ito M. Rapidly turned over protein
maintains metabotropic synaptic transmission in Purkinje cells. NeuroReport, 2000, 11(13), 2903-2906.
- Vigot R. and Batini C. Purkinje cell inhibitory responses to 3-APPA (3-
aminopropylphosphinic acid) in rat cerebellar slices. Neuroscience Research, 1999, 34(3), 141-147.
- Vigot R. and Batini C. GABAB receptor activation of Purkinje cells in cerebellar slices.
Neuroscience Research, 1997, 29, 151-160.
- Batini C., Guegan M., Palestini M., Thomasset M. and Vigot R. Upregulation of calbindin-
D-28k immunoreactivity by excitatory amino acids. Archives Italiennes de Biologie, 1997, 135, 385-397.
- Vigot R. GABAA and GABAB receptors in intact and chronically deafferented cerebellum:
pharmacological and electrophysiological study. Thesis, 1996, University Paris XI, Orsay, France, pp 158.
- Vigot R., Billard J.M. and Batini C. Reduction of GABA inhibition in Purkinje and
cerebellar nuclei neurons in climbing fibre deafferented cerebella of rat. Neuroscience Research, 1993, 17, 249-255.
- Batini C., Palestini M., Thomasset M. and Vigot R. Cytoplasmatic calcium buffer,
Calbindin-D28K, is regulated by excitatory amino acids. NeuroReport, 1993, 4, 927-930.
- Billard J.M., Vigot R. and Batini C. GABA, THIP and Baclofen inhibition of Purkinje cells
and cerebellar nuclei neurones. Neuroscience Research, 1993, 16, 65-69.

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