Thank you for registering for the $4 Co-Pay Commitment. The activated card below can be used on your next refill of EFFEXOR XR®(venlafaxine HCl) Extended-Release Capsules.
Please note a permanent card will be sent to you in the mail in 1-2 weeks.
BIN: 610020Group: 99992007ID#: 75618927704
I agree to the Terms & Conditions received with this Co-Pay card. Indications for EFFEXOR XR
EFFEXOR XR (venlafaxine HCl) Extended-Release Capsules are indicated for the treatment of Depression, Generalized Anxiety Disorder(GAD), Social Anxiety Disorder (SAD), and Panic Disorder (PD) with or without agoraphobia in adults. Important Safety Information for EFFEXOR XR Suicidality and Antidepressant Drugs Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, teens, and young adults. Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients of all ages who are started on antidepressant therapy should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior. EFFEXOR XR® (venlafaxine HCl) is not approved for use in children and teens.
People taking MAOIs should not take EFFEXOR XR.
All patients taking antidepressants should be watched closely for signs that their condition is getting worse or that they are
becoming suicidal, especially when they first start therapy, or when their dose is increased or decreased. Patients should also
be watched for becoming agitated, irritable, hostile, aggressive, impulsive, or restless. Such symptoms should be reported to
Before starting EFFEXOR XR, tell your doctor if you're taking or plan to take any prescription or over-the-counter drugs,
including migraine headache medication, herbal preparations, and nutritional supplements, to avoid a potentially life-threatening
EFFEXOR XR may raise blood pressure in some patients. Your blood pressure should be controlled before starting treatment
Taking EFFEXOR XR with aspirin, nonsteroidal anti-inflammatory drugs, warfarin, or other drugs that affect coagulation may
increase the risk of bleeding events.
Mydriasis (prolonged dilation of the pupil of the eye) has been reported with EFFEXOR XR. You should notify your physician if
you have a history of glaucoma or increased eye pressure.
When people suddenly stop using or quickly lower their daily dose of EFFEXOR XR, discontinuation symptoms may occur. Talk
to your doctor before discontinuing or reducing your dose of EFFEXOR XR.
Pregnant or nursing women shouldn't take any antidepressant without consulting their doctor.
Until you see how EFFEXOR XR affects you, be careful doing such activities as driving a car or operating machinery. Avoid
drinking alcohol while taking EFFEXOR XR.
In clinical studies, the most common side effects with EFFEXOR XR (reported in at least 10% of patients and at least twice as
often as with placebo) were constipation, dizziness, dry mouth, insomnia, loss of appetite, nausea, nervousness, sexual side
effects, sleepiness, sweating, and weakness.
Terms & Conditions By using the $4 Co-Pay Commitment Card (the "Card"), you acknowledge that you currently meet the eligibility criteria and will comply with the terms & conditions described below:
The Card is not valid for prescriptions that are eligible to be reimbursed, in whole or in part, by Medicaid, Medicare or other
federal or state healthcare programs, including any state prescription drug assistance programs and the Government Health
Insurance Plan available in Puerto Rico (formerly known as "La Reforma De Salud").
The Card is not valid for prescriptions that are eligible to be reimbursed by private insurance plans or other health or pharmacy
benefit programs that reimburse you for the entire cost of your prescription drugs.
Patients will pay a minimum of $4 per refill. By using the Card, patients will receive savings of up to $50 per refill. The Card is
good for a maximum of $700 per calendar year.
You must deduct the value received under this program from any reimbursement request submitted to your insurance plan,
either directly by you or on your behalf.
The Card is not valid for Massachusetts residents whose prescriptions are covered in whole or in part by third-party insurance, or
The Card cannot be combined with any other rebate or coupon, free trial, or similar offer for the specified prescription. The Card will be accepted only at participating pharmacies. The Card is not health insurance.
This offer is good only in the U.S. and Puerto Rico.
The Card is limited to 1 per person during this offering period and is not transferable.
Pfizer reserves the right to rescind, revoke or amend the program without notice.
The Card and Program expire on December 31, 2011.
For questions about this card, please call 877-612-1148. PATIENT INFORMATION FOR EFFEXOR XR® (venlafaxine HCl)
Be sure to read the following important information carefully. However, keep in mind that it should not take the place of your health careprofessional's instructions. If you do not understand all of this information or want to know more about EFFEXOR XR, ask your health careprofessional. What is the most important information that I should know about antidepressant medicines, depression, and other serious mental illnesses?
Antidepressant medicines may increase suicidal thoughts or actions in some children, teenagers, and young adults. However, depression andother serious mental illnesses are the most important causes of suicidal thoughts and actions. For more information, see the PrescribingInformation and the Medication Guide called Antidepressant Medicines, Depression and Other Serious Mental Illnesses, and Suicidal Thoughtsor Actions. What is the most important information that I should know about EFFEXOR XR?
Some people should not take EFFEXOR XR. Discuss this with your health care professional. People taking monoamine oxidase inhibitors(MAOIs) should not take EFFEXOR XR. MAOIs can cause a very serious reaction or even death if taken at the same time as EFFEXOR XR. You must stop taking your MAOI at least 14 days before beginning EFFEXOR XR. Similarly, you should wait 7 days after stopping EFFEXORXR before starting an MAOI. Be sure to ask your health care professional if a medicine you are taking is an MAOI.
Patients and their families should know that both adults and children taking an antidepressant medicine should be watched closely for signs thattheir condition is getting worse or that they are becoming suicidal. Pay close attention to any changes (especially sudden changes) in mood,behaviors, thoughts, or feelings. This is very important when an antidepressant medicine is started or when the dose is changed. All patientsshould be watched for becoming agitated, irritable, hostile, aggressive, impulsive, restless, or anxious. Such symptoms or any new or suddenchanges in mood, thoughts, or feelings should be reported to the patient's health care professional right away.
A life-threatening condition called serotonin syndrome or Neuroleptic Malignant Syndrome (NMS)-like reactions can happen with SNRIs andSSRIs alone, including EFFEXOR XR treatment, but particularly with concomitant use of serotonergic drugs (including medicines used to treatmigraine headaches known as triptans) or with antipsychotics or other dopamine antagonists, lithium, sibutramine, tramadol, St. John's wort,MAOIs (including linezolid, an antibiotic), and tryptophan supplements. If you take migraine headache medicines, ask your health careprofessional if your medicine is a triptan. Before you take EFFEXOR XR and any of these medicines together, talk to your health careprofessional. If you must take these medicines together, be aware of the possibility of these syndromes. Signs and symptoms of thesesyndromes may include one or more of the following: restlessness, hallucinations, loss of coordination, fast heartbeat, increased bodytemperature, muscle stiffness, increase in blood pressure, diarrhea, coma, nausea, vomiting, and confusion. Tell your health care professionalabout any medications you are taking or plan to take, including herbal preparations and nutritional supplements.
Can children take EFFEXOR XR?
EFFEXOR XR is not approved for use in children under 18. Antidepressants increased the risk of suicidal thinking and behavior (suicidality) instudies in children, teenagers, and young adults ages 18 to 24 with depression and other psychiatric disorders. For more information, see thePrescribing Information and the Medication Guide called Antidepressant Medicines, Depression and Other Serious Mental Illnesses, andSuicidal Thoughts or Actions. What is EFFEXOR XR used for?
EFFEXOR XR is a prescription medicine used to treat Depression, Generalized Anxiety Disorder (also called GAD), Social Anxiety Disorder(also called SAD), and Panic Disorder (also called PD) in adults. Depression
Symptoms of depression are different depending on the person. Some people have only a few symptoms, while others may have manysymptoms at once. Symptoms of depression include:
A sad feeling that will not go away.
Feeling worthless, or feeling guilty for no
Trouble concentrating or making decisions
A lack of interest in activities that usually
Both adults and children with depression can have their depression get worse and/or they can become suicidal. This can happen if they take anantidepressant or not. Patients treated with EFFEXOR XR should be watched closely for signs that their condition is getting worse or that theyare becoming suicidal. Such signs should be reported to their health care professional right away. Generalized Anxiety Disorder (GAD)
GAD is characterized by feelings of excessive anxiety and worry that can't be controlled and are present for at least 6 months. Other symptomsof GAD may include:
Intense self-consciousness in social settings
sweating,trembling, fast heartbeat, and nausea
Unreasonable fear of embarrassment
PD is characterized by repeated, unexpected panic attacks, followed by weeks of ongoing concern about having another panic attack. A panicattack involves rapid onset of a specific period of intense fear and discomfort that develops quickly and reaches a peak within 10 minutes. Along with these feelings, other symptoms may include:
Who should not take EFFEXOR XR?
Do not take EFFEXOR XR if you are allergic to EFFEXOR XR (venlafaxine HCl) or any of its ingredients. The inactive ingredients are cellulose,ethylcellulose, gelatin, hypromellose, iron oxide, and titanium dioxide.
EFFEXOR XR can make some conditions worse. Tell your health care professional about all your medical problems. Be sure to tell your health care professional if you have or had:
high blood pressure. EFFEXOR XR can increase your blood pressure.
heart disease. EFFEXOR XR can increase your heart rate (pulse).
liver or kidney problems. Your dose of EFFEXOR XR may need to be different.
symptoms of mania or hypomania, such as persistently elevated or irritable mood, a decreased need for sleep, racing thoughts,
hyperactivity, and rapid, excessive speech.
glaucoma. EFFEXOR XR may increase your eye pressure.
Tell your health care professional about all medicines that you are taking or plan to take, including prescription and non-prescription medicinesand supplements (including natural and herbal supplements). Taking EFFEXOR XR with aspirin, nonsteroidal anti-inflammatory drugs, warfarin,or other drugs that affect coagulation may increase the risk of bleeding events. Your health care professional will decide if you can takeEFFEXOR XR with other medicines.
EFFEXOR XR is not recommended for weight loss alone or in combination with phentermine or other products. How does EFFEXOR XR work?
EFFEXOR XR is thought to work by affecting two naturally occurring brain chemicals, serotonin and norepinephrine. This helps relieve yoursymptoms. It may take several weeks for your symptoms to get better with EFFEXOR XR. How should I take EFFEXOR XR?
EFFEXOR XR can be prescribed in different dosage strengths (37.5 mg, 75 mg, and 150 mg). The usual starting dose is 75
mg for depression, GAD, and SAD and 37.5 mg for PD, but only your health care professional can tell you which dose is right
for you and whether it will need to be adjusted over time.
EFFEXOR XR should be taken as a single dose with food at about the same time every day, either in the morning or evening.
The capsule should be swallowed whole; it should not be divided, crushed, chewed, or placed in water.
The capsule can also be carefully opened and its contents sprinkled onto a spoonful of applesauce. This should be swallowed
immediately and followed by drinking a glass of water. Do not chew this mixture before swallowing.
If you miss a dose of EFFEXOR XR, it can be taken later that day. Don't try to "make up" for the missed dose by taking two
In case of an overdose, call your health care professional or poison control center or go to the emergency room right away. What should I avoid while taking EFFEXOR XR?
Please tell your health care professional if you are pregnant, intend to become pregnant, or are breast-feeding. Some newborns whosemothers took EFFEXOR XR late in the third trimester have had problems. Because of those problems, the newborns needed long hospitalstays, help with breathing, and tube feeding. Until you see how EFFEXOR XR affects you, be careful doing such activities as driving a car oroperating machinery. Avoid drinking alcohol while taking EFFEXOR XR. EFFEXOR XR may cause other side effects besides those listedbelow. What are the possible side effects of EFFEXOR XR?
EFFEXOR XR may cause side effects in some people. In clinical studies, some people had to stop taking EFFEXOR XR because of sideeffects.
In clinical studies, the most common side effects included:
EFFEXOR XR may cause an increase in your cholesterol. Your health care professional may want to do blood tests to check your serumcholesterol periodically. Tell your health care professional right away if you have:
increases in blood pressure or heart rate.
extreme confusion, unsteadiness, or seizures, which may indicate very low levels of sodium in the blood.
sudden, unexpected eye pain, eye redness, or changes in vision, which may indicate increased eye pressure.
symptoms of mania or hypomania, such as persistently elevated or irritable mood, a decreased need for sleep, racing thoughts,
hyperactivity, and rapid, excessive speech.
signs and symptoms of serotonin syndrome or Neuroleptic Malignant Syndrome-like reactions, which may include a combination
of the following: restlessness, hallucinations, loss of coordination, fast heartbeat, increased body temperature, fast changes in
blood pressure, overactive reflexes, diarrhea, coma, nausea, vomiting, muscle stiffness, and confusion.
EFFEXOR XR may cause an increase in your blood pressure. Your health care professional may want your blood pressure to be checkedmore often.
EFFEXOR XR may increase your eye pressure. You may need more frequent eye exams to detect an increase in eye pressure.
For more information on these and other side effects associated with EFFEXOR XR, talk to your health care professional or visit our website at www.EFFEXORXR.com. What happens when I stop using EFFEXOR XR?
Symptoms are known to occur when people stop using EFFEXOR XR, especially when they suddenly stop therapy.
When people suddenly stop using EFFEXOR XR, they can get symptoms from stopping the medicine too fast. Some of these symptomsinclude:
Do not stop taking EFFEXOR XR without talking with your health care professional first. Your health care professional may want to slowlydecrease your dose of EFFEXOR XR to help avoid these kinds of symptoms. General advice about EFFEXOR XR
Medicines are sometimes prescribed for conditions that are not mentioned in patient information leaflets. Do not use EFFEXOR XR for acondition that has not been prescribed by your health care professional. Do not give EFFEXOR XR to other people, even if they have the samesymptoms you have. It may harm them.
This is a summary of the most important information about EFFEXOR XR. If you would like more information, talk with your (or your familymember's) health care professional about all the risks and benefits of antidepressant medicines and all treatment choices for depression orother serious mental illnesses. You can ask your health care professional for information about EFFEXOR XR that is written for healthprofessionals. What are the ingredients in EFFEXOR XR?
EFFEXOR XR contains venlafaxine hydrochloride, an antidepressant. Inactive ingredients consist of cellulose, ethylcellulose, gelatin,hypromellose, iron oxide, and titanium dioxide. How do I store EFFEXOR XR?
Store EFFEXOR XR at room temperature (68° to 77°F or 20° to 25°C). Keep EFFEXOR XR away from children. For more information on EFFEXOR XR
This page is only a summary. For more complete information, talk to your health care professional. You can also go to www.EFFEXORXR.com.
This brief summary is based on EFFEXOR XR Prescribing Information W10404C040, revised July 2009.
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Com base nas circunstâncias fáticas e processuais abaixo descritas, equacione a questão, prolatando a peça adequada. 1. Em 9.3.2011, com o objetivo de averiguar diversas denúncias formuladas por vizinhos a respeito de ruídos excessivos causados pelo uso ilícito de equipamentos mecânicos, a Policia Militar, com atribuição respectiva, dirigiu-se ao sítio de Everton Jacob , situad